ID A0A3N6LPF6_9EURY Unreviewed; 567 AA.
AC A0A3N6LPF6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Potassium transporter Kef {ECO:0000313|EMBL:RQG90017.1};
GN ORFNames=EA462_08405 {ECO:0000313|EMBL:RQG90017.1};
OS Natrarchaeobius halalkaliphilus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrarchaeobius.
OX NCBI_TaxID=1679091 {ECO:0000313|EMBL:RQG90017.1, ECO:0000313|Proteomes:UP000273828};
RN [1] {ECO:0000313|EMBL:RQG90017.1, ECO:0000313|Proteomes:UP000273828}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AArcht-Sl {ECO:0000313|EMBL:RQG90017.1,
RC ECO:0000313|Proteomes:UP000273828};
RA Sorokin D.Y., Elcheninov A.G., Kostrikina N.A., Bale N.J.,
RA Sinninghe Damste J.S., Khijniak T.V., Kublanov I.V., Toshchakov S.V.;
RT "Natrarchaeobius chitinivorans gen. nov., sp. nov., and Natrarchaeobius
RT haloalkaliphilus sp. nov., alkaliphilic, chitin-utilizing haloarchaea from
RT hypersaline alkaline lakes.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RQG90017.1}.
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DR EMBL; REFY01000003; RQG90017.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N6LPF6; -.
DR OrthoDB; 43518at2157; -.
DR Proteomes; UP000273828; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR42751:SF3; NA(+)_H(+) ANTIPORTER; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000273828};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 410..493
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 567 AA; 62300 MW; 25C922EF82FFABF9 CRC64;
MPLEEIAVSA DFALLLASAA ILGYVARLTK QPTIVAYVLT GVVIGPIGLG LITGESGLIE
VIAELGLGFL LFLLGIKMSF EDIKEIMRPV GKIAVGQAIL QAVASTTLAL LLGFTLYQSL
ILALATTFGA TPIIVKVLSD KDELKSLYGR VDIGVLIFQD IYLVFALAIL AVGTVDSAEQ
IAFSISRVIV LMIVMGVGAY LASKYVLPTL LRASATNKSA LFTVGIAWAF VFIYAAEVLD
LSVELGAFIA GLALANLPYS TELKEQMRPV TDLFIAVFFA SIALQMERGQ LLVYWQEAVI
ASFALLTINF FIVFGLFYSQ KFDMETSFLG TISMLQVSEF SIVLGALAVN EGFVAEAILG
FLSLMALITM PISTYYVIYN REIYERVRPY LERFEHDDPI EFDPLTYENH AVIVGYDGVT
GRLTETLENR FEDVVFVEDQ RERIETLRRK DLEFIFGDSR HGEIRKDANV REAALVLSTL
DRTDINRRLI EDAGNADVIV LANDEADANE LEQTGASHVI REQQLLEDAV STILAGVDDE
GTIGEKNDVI RWKNEAGTRS REGDFDV
//
