ID   A0A3N6M9Q1_9EURY        Unreviewed;       385 AA.
AC   A0A3N6M9Q1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Arsenical-resistance protein {ECO:0000313|EMBL:RQG93030.1};
GN   Name=arsB {ECO:0000313|EMBL:RQG93030.1};
GN   ORFNames=EA462_02115 {ECO:0000313|EMBL:RQG93030.1};
OS   Natrarchaeobius halalkaliphilus.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrarchaeobius.
OX   NCBI_TaxID=1679091 {ECO:0000313|EMBL:RQG93030.1, ECO:0000313|Proteomes:UP000273828};
RN   [1] {ECO:0000313|EMBL:RQG93030.1, ECO:0000313|Proteomes:UP000273828}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AArcht-Sl {ECO:0000313|EMBL:RQG93030.1,
RC   ECO:0000313|Proteomes:UP000273828};
RA   Sorokin D.Y., Elcheninov A.G., Kostrikina N.A., Bale N.J.,
RA   Sinninghe Damste J.S., Khijniak T.V., Kublanov I.V., Toshchakov S.V.;
RT   "Natrarchaeobius chitinivorans gen. nov., sp. nov., and Natrarchaeobius
RT   haloalkaliphilus sp. nov., alkaliphilic, chitin-utilizing haloarchaea from
RT   hypersaline alkaline lakes.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC       family. {ECO:0000256|ARBA:ARBA00010110}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RQG93030.1}.
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DR   EMBL; REFY01000001; RQG93030.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N6M9Q1; -.
DR   Proteomes; UP000273828; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR004706; Arsenical-R_Acr3.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   NCBIfam; TIGR00832; acr3; 1.
DR   PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR   PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PIRSF; PIRSF005508; Acr3; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000273828};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        29..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        202..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        274..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   385 AA;  41606 MW;  C2BFF336C0EE3652 CRC64;
     MRDAHDHGPN CDCGSCGDPR AMDVLDKYLT VWIFAAMAVG VGLGYVAPGV VDPIREYSLV
     ELGLILMMYP PLAKVNYRRL PTVFSQWRIL SLSLLQNWLI GPTVMFLLAV IFFSGAVPWF
     PARPEYFLGL IFIGMARCIA MVLVWNDLAD GSSEYAAGLV AFNSVFQIVT YGVYIWAFAL
     VLPPLLGLDA LASGISAFDI TTMQVFEAIV IFLGIPFAAG MLTRFGGVRA RGEAWYADEL
     VPKISPLTLL ALLFTIVVMF ATQGDAIVAQ PTDVLWIAVP LTIYFVVMFL VSFAMGRGIG
     ADYSTTTAIG FTAASNNFEL AIAVAVAVFG IGSGVAFATV VGPLIEVPVL LALVHVALYF
     GRRFDWDGFE TGRLDGSPSE TTTDD
//