ID   A0A3N6N6N3_9BURK        Unreviewed;       441 AA.
AC   A0A3N6N6N3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:RQH06391.1};
GN   ORFNames=D1Y85_10900 {ECO:0000313|EMBL:RQH06391.1};
OS   Paraburkholderia dinghuensis.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=2305225 {ECO:0000313|EMBL:RQH06391.1, ECO:0000313|Proteomes:UP000272778};
RN   [1] {ECO:0000313|EMBL:RQH06391.1, ECO:0000313|Proteomes:UP000272778}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DHOA04 {ECO:0000313|EMBL:RQH06391.1,
RC   ECO:0000313|Proteomes:UP000272778};
RA   Gao Z.-H., Qiu L.-H., Fu J.-C.;
RT   "Paraburkholderia sp. DHOA04, isolated from soil.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RQH06391.1}.
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DR   EMBL; RQIS01000007; RQH06391.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N6N6N3; -.
DR   OrthoDB; 5287258at2; -.
DR   Proteomes; UP000272778; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1040.50; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR23309; 3-HYDROXYACYL-COA DEHYROGENASE; 1.
DR   PANTHER; PTHR23309:SF9; PEROXISOMAL BIFUNCTIONAL ENZYME; 1.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000272778}.
FT   DOMAIN          42..218
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          222..315
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   DOMAIN          351..434
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   441 AA;  48472 MW;  822BF3453C659535 CRC64;
     MNAPAELTLQ ENAALAHVKA AEKAAAKIPV GVDVKPLEIR QAAVIGAGTM GGGIAMALVA
     AGIPVVLVDA NDEGLQRGLR RIRDNYDGSI KRGKLDEAMR DQRMALITGT TAIADVKDAD
     IIIEAVFEDL GLKQGIFREL DQHARTGAIL ATNTSGLDID EIAGVTKRPQ DVVGAHFFSP
     AHVMRLLEVV QADKTSDEAV VTLMELGRRM GKVSVYAKVY PGFIGNALFR NYNREAHFLV
     EDGALPHEVD AALKDFGYAM GIFAVHDMAG NDVGYQTRKA QMATRPTDRR WNDLIMKLTE
     MGRLGQKSGK GWYRYEAGDR TPHRDPEVER YIVEESARMG ITRRPISQEE IIKRCMYGMI
     NEGAKLLEQG IALRASDIDI VYVTGYGFPA RKGGPMYYAD QIGLANVCAD IKRLYEEYGY
     WWKPAPLLAK LAAENGRFAD L
//