ID A0A3N6NZW9_9CYAN Unreviewed; 288 AA.
AC A0A3N6NZW9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Methyltransferase domain-containing protein {ECO:0000313|EMBL:RQH57519.1};
GN ORFNames=D5R40_00660 {ECO:0000313|EMBL:RQH57519.1};
OS Okeania hirsuta.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Okeania.
OX NCBI_TaxID=1458930 {ECO:0000313|EMBL:RQH57519.1, ECO:0000313|Proteomes:UP000269154};
RN [1] {ECO:0000313|EMBL:RQH57519.1, ECO:0000313|Proteomes:UP000269154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAB10Feb10-1 {ECO:0000313|EMBL:RQH57519.1,
RC ECO:0000313|Proteomes:UP000269154};
RX PubMed=30444349;
RA Moss N.A., Leao T., Rankin M., McCullough T.M., Qu P., Korobeynikov A.,
RA Smith J.L., Gerwick L., Gerwick W.H.;
RT "Ketoreductase domain dysfunction expands chemodiversity: malyngamide
RT biosynthesis in the cyanobacterium Okeania hirsuta.";
RL ACS Chem. Biol. 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. gTMT family. {ECO:0000256|PROSITE-ProRule:PRU00914}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RQH57519.1}.
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DR EMBL; RCBY01000002; RQH57519.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N6NZW9; -.
DR OrthoDB; 9769602at2; -.
DR Proteomes; UP000269154; Unassembled WGS sequence.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR025774; MTs_g-TMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR44068:SF11; GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR44068; ZGC:194242; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51581; SAM_GTMT; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00914,
KW ECO:0000313|EMBL:RQH57519.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000269154};
KW S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU00914};
KW Transferase {ECO:0000256|PROSITE-ProRule:PRU00914,
KW ECO:0000313|EMBL:RQH57519.1}.
FT DOMAIN 73..171
FT /note="Methyltransferase type 11"
FT /evidence="ECO:0000259|Pfam:PF08241"
FT REGION 72..81
FT /note="SAM motif I"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00914"
FT REGION 135..143
FT /note="SAM motif II"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00914"
FT REGION 162..171
FT /note="SAM motif III"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00914"
SQ SEQUENCE 288 AA; 32360 MW; F756866942AB4826 CRC64;
MTSNLIEQIQ QFYDASSSLW EQAWGEHMHH GHYGQDGKQK KNRRQAQIDM IEELLQWGAL
NEKSNFWPPT SILDVGCGIG GSTLYLAEKF HATATGITLS PVQAQRAKER ADVANLSQTT
NFIVANALEM PFADESFDLV WSLESGEHMP NKQKFLQECH RVLKPGGTII MATWCHRPVG
SSYGQLTDDE RRHLAEIYRV YALPYVISLP EYEAIAQNVG FQNICTADWS TAAAPFWNIV
IESAFDPKVI MNLLFSGWTT IQAALSLELM SSGYERGLIK FGLVRGNK
//
