ID A0A3N6PT37_9BURK Unreviewed; 513 AA.
AC A0A3N6PT37;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Hopanoid C-3 methylase HpnR {ECO:0000313|EMBL:RQH02776.1};
GN Name=hpnR {ECO:0000313|EMBL:RQH02776.1};
GN ORFNames=D1Y85_21855 {ECO:0000313|EMBL:RQH02776.1};
OS Paraburkholderia dinghuensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=2305225 {ECO:0000313|EMBL:RQH02776.1, ECO:0000313|Proteomes:UP000272778};
RN [1] {ECO:0000313|EMBL:RQH02776.1, ECO:0000313|Proteomes:UP000272778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DHOA04 {ECO:0000313|EMBL:RQH02776.1,
RC ECO:0000313|Proteomes:UP000272778};
RA Gao Z.-H., Qiu L.-H., Fu J.-C.;
RT "Paraburkholderia sp. DHOA04, isolated from soil.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RQH02776.1}.
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DR EMBL; RQIS01000018; RQH02776.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N6PT37; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000272778; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR027564; HpnR_B12_rSAM.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04367; HpnR_B12_rSAM; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF17; MG-PROTOPORPHYRIN IX MONOMETHYL ESTER OXIDATIVE CYCLASE 66KD SUBUNIT; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDF00565; hopanoid_C3-methyltransferase; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:RQH02776.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000272778};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:RQH02776.1}.
FT DOMAIN 8..141
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 180..394
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
FT REGION 490..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 57858 MW; FE14E6D60B62511C CRC64;
MRLLAVHPSG LMYTRVFLRL EPLGLESVAG VARAAGHDVR LLDLQVQTHR DLMRLVRAWQ
PEALCFSGNY LANIPEIIDL SKAVKTALPS CFVFVGGHSV SFTAGELLRH AEGAIDCVLR
GEGEASIAAL LEAVGGGDLL AVPGVVTRDG SGPPPGFLEH LDSVQPARDL LRHRRKYFIG
TLDPCASIEF ARGCPWDCTF CSAWTFYGRS YRTRSPEVVV EELAALREPG VFIVDDVAFV
HAEHGMAIGE AIQRRGINKE YYLETRGDVL LRNKEVFALW QRLGLRYMFL GLEAIDEEGL
KMFRKRVSLD RNFEALEFAR SLGITVAINL IADPDWDHDR FETIRKWCME IPEIVNISVN
TPYPGTESWQ RESRRLTSLD YRLYDIQHAV VPTKLPLPEF YAELVRTQQV LNRKHMGWGA
LRRASGVAAR LLMHGQINFV RMLWRFNSVF DPRLQLADHE REVRYEMAPP PATGSERRVD
MKTIYIHGPA GRSSRKIDDA TESFVDETRT GTG
//
