ID   A0A3N6PWB6_9BURK        Unreviewed;       562 AA.
AC   A0A3N6PWB6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Aspartate-alanine antiporter {ECO:0000313|EMBL:RQH04166.1};
GN   Name=aspT {ECO:0000313|EMBL:RQH04166.1};
GN   ORFNames=D1Y85_18920 {ECO:0000313|EMBL:RQH04166.1};
OS   Paraburkholderia dinghuensis.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=2305225 {ECO:0000313|EMBL:RQH04166.1, ECO:0000313|Proteomes:UP000272778};
RN   [1] {ECO:0000313|EMBL:RQH04166.1, ECO:0000313|Proteomes:UP000272778}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DHOA04 {ECO:0000313|EMBL:RQH04166.1,
RC   ECO:0000313|Proteomes:UP000272778};
RA   Gao Z.-H., Qiu L.-H., Fu J.-C.;
RT   "Paraburkholderia sp. DHOA04, isolated from soil.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000256|ARBA:ARBA00009854}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RQH04166.1}.
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DR   EMBL; RQIS01000014; RQH04166.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N6PWB6; -.
DR   OrthoDB; 8611026at2; -.
DR   Proteomes; UP000272778; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR   InterPro; IPR022457; Asp_Ala_antiprt.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   NCBIfam; TIGR03802; Asp_Ala_antiprt; 1.
DR   NCBIfam; TIGR01625; YidE_YbjL_dupl; 1.
DR   PANTHER; PTHR30445:SF8; TRANSPORT PROTEIN YBJL-RELATED; 1.
DR   PANTHER; PTHR30445; UNCHARACTERIZED; 1.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS51202; RCK_C; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000272778};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        62..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        451..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        480..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          206..290
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   562 AA;  59195 MW;  34DC10BD157B3E06 CRC64;
     MEWLHRIFQR SPEIALFLSL AIGYWVGQIR FGKFQFGGVG GTLLAAIVIS QVGVTVDNGV
     KSVMFAVFIY AVGYQSGPGF VSSLNRKSLR EIAMSAFMAF AGLITVLVCA KLFHLNKGLA
     AGLAAGGMTQ SAIIGTAGDA IAHLGLSADQ VKSMQADVAV GYAVTYVFGT LGAIIVCVNI
     LPRILGQGLK EASIEAEQAM SGSAEPAMGP GMVSALPELF GRVFRVDSGA GKTIKQIELA
     EHDMVVIEKV SRAGEPVEPA PEFVLSRDDI VLVVGHRKQM VEVGARLGPE VPDSGGLSLV
     MRTRRAVFTA EGMNHTTIAE LRKSVERQLR HGVYIESITR AGQSVPVLPE TRVEHGDVMT
     FYGTAADTKR AALAAGYEME YTYKTDLIYM GVGLALGLLI GLIVIHISGI PLTLGSGGGC
     LVSGLLFGWM RGKYPMYGVM PAAASQLLRD FGLTAFVAVV GLNAGLQAEV TIRQSGVTLF
     LLGVVVTIVP LLLTLLFGRY VLRYDNAAML AGALAGSRSS NPAFGGVLDK AESSVPTVPF
     AITYTIANVL LTLLGPLVVG LA
//