ID A0A3N7BNX3_9BURK Unreviewed; 450 AA.
AC A0A3N7BNX3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cobalamin biosynthesis bifunctional protein CbiET {ECO:0000313|EMBL:RQO54427.1};
GN ORFNames=DBR47_22530 {ECO:0000313|EMBL:RQO54427.1};
OS Paucibacter sp. KBW04.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Roseateles.
OX NCBI_TaxID=2153361 {ECO:0000313|EMBL:RQO54427.1, ECO:0000313|Proteomes:UP000274884};
RN [1] {ECO:0000313|EMBL:RQO54427.1, ECO:0000313|Proteomes:UP000274884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBW04 {ECO:0000313|EMBL:RQO54427.1,
RC ECO:0000313|Proteomes:UP000274884};
RA Lee F., Williams K.B., Levin M., Wolfe B.E.;
RT "The microbiome of the planarian worm Dugesia japonica mediates outcomes of
RT regeneration via indole production.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RQO54427.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QAJN01000019; RQO54427.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N7BNX3; -.
DR OrthoDB; 9787825at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000274884; Unassembled WGS sequence.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000274884};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 29..225
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 450 AA; 48652 MW; E096E4DF240D0B4E CRC64;
MDSIQEDVIV GEDLTYEGQR FTRGPRCRVI GVLDDGAASL SSLALAHLRE AECVIGASRT
LALLEAQIAP TAQRLDLGEG LSQVPEWVRQ AQAQGRRCVV LATGDPLFFG IASYLAARLC
VDALEVLPNL STVQIACARL GLPWQSIKLC SIHARDAGEW RVGAEASHGL YELMQTLRSH
ERVAVLTSPD NSPDRIARML LAEGLGEEFQ LAVAESLCQP GERVRAELSA AEVAQMRFAE
LNIVLLLRLK PRPRPVLLGL ADSNYEQRQP EKGLITKQEV RAVSLARMQL RADSIVWDIG
AGSGSVGLEA ARLCSEGHVY AIEKNAEDFA IAGRNHRAMA LSNYSLQQGR APEGLDAWAD
PDAVFVGGSG GELAQLIARI LARLKPQGML VMNFVTIENL GTAVEALNAS GAQWDVLQLQ
ASRSKPILHM HRMAAENPVW IVCAQSGAKP
//
