ID A0A3N7J4K6_9BURK Unreviewed; 255 AA.
AC A0A3N7J4K6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=uroporphyrinogen-III C-methyltransferase {ECO:0000256|ARBA:ARBA00012162};
DE EC=2.1.1.107 {ECO:0000256|ARBA:ARBA00012162};
GN Name=cobA {ECO:0000313|EMBL:RQP25772.1};
GN ORFNames=DZC73_01495 {ECO:0000313|EMBL:RQP25772.1};
OS Albitalea terrae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Albitalea.
OX NCBI_TaxID=2496871 {ECO:0000313|EMBL:RQP25772.1, ECO:0000313|Proteomes:UP000267464};
RN [1] {ECO:0000313|EMBL:RQP25772.1, ECO:0000313|Proteomes:UP000267464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S-16 {ECO:0000313|EMBL:RQP25772.1,
RC ECO:0000313|Proteomes:UP000267464};
RA Khan S.A., Jeon C.O., Chun B.H., Jeong S.E.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RQP25772.1, ECO:0000313|Proteomes:UP000267464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S-16 {ECO:0000313|EMBL:RQP25772.1,
RC ECO:0000313|Proteomes:UP000267464};
RA Shunsuke S.S.;
RT "Rhizobacter gummiphilus sp. nov., a rubber-degrading bacterium isolated
RT from the soil of a botanical garden in Japan.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Porphyrin-containing compound metabolism; siroheme
CC biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.
CC {ECO:0000256|ARBA:ARBA00025705}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RQP25772.1}.
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DR EMBL; QUSW01000001; RQP25772.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N7J4K6; -.
DR OrthoDB; 9815856at2; -.
DR UniPathway; UPA00262; UER00211.
DR Proteomes; UP000267464; Unassembled WGS sequence.
DR GO; GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0019354; P:siroheme biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd11642; SUMT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006366; CobA/CysG_C.
DR InterPro; IPR003043; Uropor_MeTrfase_CS.
DR NCBIfam; TIGR01469; cobA_cysG_Cterm; 1.
DR PANTHER; PTHR45790:SF3; S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
DR PROSITE; PS00839; SUMT_1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:RQP25772.1};
KW Porphyrin biosynthesis {ECO:0000256|ARBA:ARBA00023244};
KW Reference proteome {ECO:0000313|Proteomes:UP000267464};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RQP25772.1}.
FT DOMAIN 4..199
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 255 AA; 26858 MW; B5478DD809523A75 CRC64;
MAGRVVFIGA GPGSADLITL RGARLLGDAD VVLHDALTDP ALREFAPRAR WIHVGKRGFS
DSTGQDLINA MLVKHAAEVA LVVRLKGGDP SIFGRLEEEL DAMARAGIEC EVVPGVTAAI
AAAAATQRPL TRRGDGRSVS FTTAMTRTGD MHASRTADTE VFYMAGKQLC ALSRRLIEAG
WPSDTPVSVV SRAGWPDQLH SDHNVATLPR ASLLHAGRPT IVTVGAGARP LEACQEPAKR
NASDAAVTCE PCPKP
//
