ID A0A3N9TFQ9_9VIBR Unreviewed; 857 AA.
AC A0A3N9TFQ9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Chaperone protein ClpB {ECO:0000256|ARBA:ARBA00017574, ECO:0000256|RuleBase:RU362034};
GN Name=clpB {ECO:0000256|RuleBase:RU362034,
GN ECO:0000313|EMBL:RQW63087.1};
GN ORFNames=EES38_12320 {ECO:0000313|EMBL:RQW63087.1};
OS Vibrio viridaestus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=2487322 {ECO:0000313|EMBL:RQW63087.1, ECO:0000313|Proteomes:UP000281112};
RN [1] {ECO:0000313|EMBL:RQW63087.1, ECO:0000313|Proteomes:UP000281112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LJC006 {ECO:0000313|EMBL:RQW63087.1,
RC ECO:0000313|Proteomes:UP000281112};
RA Liang J.;
RT "Vibrio LJC006 sp. nov., isolated from seawater during the bloom of the
RT enteromorpha.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of a stress-induced multi-chaperone system, it is
CC involved in the recovery of the cell from heat-induced damage, in
CC cooperation with DnaK, DnaJ and GrpE. {ECO:0000256|RuleBase:RU362034}.
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SUBUNIT: Homohexamer; The oligomerization is ATP-dependent.
CC {ECO:0000256|RuleBase:RU362034}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU362034}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RQW63087.1}.
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DR EMBL; RJVQ01000004; RQW63087.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N9TFQ9; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000281112; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule.
DR GO; GO:0009408; P:response to heat; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR017730; Chaperonin_ClpB.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03346; chaperone_ClpB; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362034};
KW Cytoplasm {ECO:0000256|RuleBase:RU362034};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000281112};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}; Stress response {ECO:0000256|RuleBase:RU362034}.
FT DOMAIN 3..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT COILED 405..461
FT /evidence="ECO:0000256|RuleBase:RU362034"
SQ SEQUENCE 857 AA; 96098 MW; 5DFC1FF9CA2A3B1F CRC64;
MRLDRFTSKF QVAISDAQSL ALGRDHQYIE PVHLMVALMD QDGSPIRPLL TMMNVDAMQL
RSKLGEELDR LPKVTGIGAD VQLSSGLGYL FNMCDKIAQK RQDAYISSEI FLLAAIQDKG
PLGQLCKDLG VTEKKVTDAI EKVRGGQKVK DQNAEDLRQA LEKFTVDLTE RAEQGKLDPV
IGRDDEIRRT IQVLQRRTKN NPVLIGEPGV GKTAIVEGLA QRIINNEVPE GLRGRRVLSL
DMGALVAGAK YRGEFEERLK SVLNELAKEE GNVILFIDEL HTMVGAGKGE GSMDAGNMLK
PALARGELHC VGATTLDEYR QYVEKDPALE RRFQKVLVDE PSVEDTVAIL RGLKERYELH
HHVEITDPAI VAAATLSHRY VSDRQLPDKA IDLIDEAASS IRLQIDSKPE ELDKLERRII
QLKIEQQALS NEHDNASNKR LEILNEELTE REKEYAELEE VWNAEKAALS GTQHIKSELE
QARMDMDVAR RAGDLNRMSE LQYGRIPELE KQLDLAAQAE MQEMTLLRNK VTDAEIAEVL
SKQTGIPVSK MLEAEKEKLL QMESVLHKRV IGQVEAVDVV SNAIRRSRAG LSDPNRPIGS
FLFLGPTGVG KTELCKTLAN FMFDSEEAMV RIDMSEFMEK HSVARLVGAP PGYVGYEEGG
YLTEAVRRKP YSVILLDEVE KAHPDVFNIL LQVLDDGRLT DGQGRTVDFR NTVVIMTSNL
GSSQIQEGFK DLNYEQMKAQ VMDVVAHHFR PEFLNRVDES VVFHPLGREQ IKSIASIQIE
RLRQRMHERD YELDMDEKAL DLIAQVGFDP VYGARPLKRA IQQEVENPLA KAMLSGEFTP
GRPIKLTAVD GKILATQ
//
