ID A0A3P1W290_9FUSO Unreviewed; 430 AA.
AC A0A3P1W290;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Citrate lyase holo-[acyl-carrier protein] synthase {ECO:0000313|EMBL:RRD40692.1};
DE EC=2.7.7.61 {ECO:0000313|EMBL:RRD40692.1};
GN Name=citX {ECO:0000313|EMBL:RRD40692.1};
GN ORFNames=EII29_01810 {ECO:0000313|EMBL:RRD40692.1};
OS Leptotrichia sp. OH3620_COT-345.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Leptotrichiaceae;
OC Leptotrichia.
OX NCBI_TaxID=2491048 {ECO:0000313|EMBL:RRD40692.1, ECO:0000313|Proteomes:UP000280115};
RN [1] {ECO:0000313|EMBL:RRD40692.1, ECO:0000313|Proteomes:UP000280115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OH3620_COT-345 {ECO:0000313|EMBL:RRD40692.1,
RC ECO:0000313|Proteomes:UP000280115};
RA Coil D.A., Jospin G., Darling A.E., Wallis C., Davis I.J., Harris S.,
RA Eisen J.A., Holcombe L.J., O'Flynn C.;
RT "Genomes From Bacteria Associated with the Canine Oral Cavity: a Test Case
RT for Automated Genome-Based Taxonomic Assignment.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-
CC [citrate lyase ACP] = diphosphate + holo-[citrate lyase ACP];
CC Xref=Rhea:RHEA:16333, Rhea:RHEA-COMP:10157, Rhea:RHEA-COMP:10158,
CC ChEBI:CHEBI:29999, ChEBI:CHEBI:33019, ChEBI:CHEBI:61378,
CC ChEBI:CHEBI:82683; EC=2.7.7.61;
CC Evidence={ECO:0000256|ARBA:ARBA00000145};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3'-dephospho-CoA + ATP = 2'-(5''-triphospho-alpha-D-ribosyl)-
CC 3'-dephospho-CoA + adenine; Xref=Rhea:RHEA:15117, ChEBI:CHEBI:16708,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57328, ChEBI:CHEBI:61378; EC=2.4.2.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001210};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRD40692.1}.
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DR EMBL; RQYW01000002; RRD40692.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P1W290; -.
DR OrthoDB; 114886at2; -.
DR Proteomes; UP000280115; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0050519; F:holo-citrate lyase synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046917; F:triphosphoribosyl-dephospho-CoA synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR GO; GO:0051191; P:prosthetic group biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.4200.10; Triphosphoribosyl-dephospho-CoA protein; 1.
DR InterPro; IPR002736; CitG.
DR InterPro; IPR005551; CitX.
DR NCBIfam; TIGR03124; citrate_citX; 1.
DR PANTHER; PTHR30201:SF2; 2-(5''-TRIPHOSPHORIBOSYL)-3'-DEPHOSPHOCOENZYME-A SYNTHASE; 1.
DR PANTHER; PTHR30201; TRIPHOSPHORIBOSYL-DEPHOSPHO-COA SYNTHASE; 1.
DR Pfam; PF01874; CitG; 1.
DR Pfam; PF03802; CitX; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:RRD40692.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:RRD40692.1};
KW Transferase {ECO:0000313|EMBL:RRD40692.1}.
SQ SEQUENCE 430 AA; 49559 MW; BA1CA1E5063D3627 CRC64;
MNIGNFLNDR EKRVEYQKKL IEKYKKTLVV LKANFPGKNK NLPLADNIVD AISEEIDKLF
EKNIIFRENF RNEEGKFFFY ILEGNAYNIK KSMIILEESH ELGRCADIDV HTPEGNVLSR
KDIGNSFRKC FLCNDKAYNC VRSMKHSYEE LYNFLEEKYR NYIAHKFSLA ALEGLIYEVS
AYPSFGLVSP VNTGSHKDMN FYTFLESGFA IEKAFYEITR IGYSDIELDT AFSIAREIGK
KAEISMMRAT KNVNTHKGLI FLMGITVLAT ARNFYLGKNI EKIPELIRKI TKNILDDFKN
IGNKENLTNG EKLYVKYGFT GIRGEVREGL TGIFDDILPF YDENLKCYSK NTVCSMTLIK
LMNIINDSTI VHRHGIEMLS EVKKRTKSLI GISEKEKLEK FEKWCIENNI SPGGSADVLA
VVIFLHNIYY
//
