ID A0A3P1WI68_9ACTN Unreviewed; 960 AA.
AC A0A3P1WI68;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase {ECO:0000313|EMBL:RRD46011.1};
DE EC=2.7.7.42 {ECO:0000313|EMBL:RRD46011.1};
DE EC=2.7.7.89 {ECO:0000313|EMBL:RRD46011.1};
GN ORFNames=EII42_09215 {ECO:0000313|EMBL:RRD46011.1};
OS Tessaracoccus sp. OH4464_COT-324.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Tessaracoccus.
OX NCBI_TaxID=2491059 {ECO:0000313|EMBL:RRD46011.1, ECO:0000313|Proteomes:UP000274803};
RN [1] {ECO:0000313|EMBL:RRD46011.1, ECO:0000313|Proteomes:UP000274803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OH4464_COT-324 {ECO:0000313|EMBL:RRD46011.1,
RC ECO:0000313|Proteomes:UP000274803};
RA Coil D.A., Jospin G., Darling A.E., Wallis C., Davis I.J., Harris S.,
RA Eisen J.A., Holcombe L.J., O'Flynn C.;
RT "Genomes From Bacteria Associated with the Canine Oral Cavity: a Test Case
RT for Automated Genome-Based Taxonomic Assignment.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRD46011.1}.
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DR EMBL; RQYZ01000016; RRD46011.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P1WI68; -.
DR OrthoDB; 9759366at2; -.
DR Proteomes; UP000274803; Unassembled WGS sequence.
DR GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0047388; F:[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR023057; GlnE.
DR InterPro; IPR005190; GlnE_rpt_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF08335; GlnD_UR_UTase; 2.
DR Pfam; PF03710; GlnE; 2.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:RRD46011.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000274803};
KW Transferase {ECO:0000313|EMBL:RRD46011.1}.
FT DOMAIN 75..309
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 333..461
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
FT DOMAIN 569..793
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 830..948
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
SQ SEQUENCE 960 AA; 104795 MW; E1C6C07AB4A7F689 CRC64;
MGRIQSSSAE FARRGFESAT AAARIWDAWP AEQRAMVDLA LFGRVGDRFQ ALETLDRLRA
TDRFEAIAAD PGWLERVLRV AGASSVLAAG LRTSPETVQL LAEEPRERDE RAWAAFFQAR
VPVVDGECHR HPDELRSANR AALTLIAARD LAADDPTEIV EGVARELSHV ADCVLETSLA
LARAETPGWQ AARLAIVALG KAGGQELNYL SDVDVLYIAE PTEGADPDEA AAIANRVAAA
QARICSAHTK AGTIWSVDAS LRPEGKAGPL VRSLASCRRY YDQWAENWEF QALLKARPAA
GDLGLGEAFI DLVSPLVWRS GERPGFLPEM RAMRERVIAH IPDKQAETEI KLSEGGLRDT
EFSVQLLQLV HGRADDRIRD RGTLPALRSL VSCGYIGRSD GSQLAQHYRF QRVLEHRAQL
VNLRRTHVVP DDDRLAQFAR AGLDDARARW RTSRRDVRRL RQRIFFSPLL DTVVSLPADT
LLSPDAVKER MRALGFNDPR TALGHMQALT AGTSRAAEIL RQLMPAMLEW IALGPNPDFG
LLAFRQLCET LGESPWFLRG LRDEGYMATR LAKVASTSRF TVDLLKRAPD TVGLLASDEA
LTPRSAAELG VAMGRSAARH ADLARALDSA RAFRRSELCR VALRDVLGGV DIVECGRALS
ALASATVQTA LDIARRAVDA PELGIIALGR WGGEEMSYAS DLDCIFVVAD DAGPAGLAAA
TELVRELARI LKQPGVEGIT LDADLRPEGK GGPQVRTVSS YRKYYERWGA VWEAQMLLRA
RHGAGSAELV QAVLDDIDPV RYPERLTDDA VREIRRLKSR MERERIPAGV DPSRHLKLGP
GGLSDIEWTI QLIQLAHAHR HPELRTTSTL GALAAARALG LVAPGDADAL SAAWRHASTV
RDAIMLVRGR PSDALPTNTR ELAAVAALLG HDAPVAELGE NTRRHARLAG AVVGRLFWGE
//
