ID A0A3P1XUE2_9MICO Unreviewed; 438 AA.
AC A0A3P1XUE2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=EII30_02125 {ECO:0000313|EMBL:RRD61646.1};
OS Leucobacter sp. OH1287.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leucobacter.
OX NCBI_TaxID=2491049 {ECO:0000313|EMBL:RRD61646.1, ECO:0000313|Proteomes:UP000281351};
RN [1] {ECO:0000313|EMBL:RRD61646.1, ECO:0000313|Proteomes:UP000281351}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OH1287 {ECO:0000313|EMBL:RRD61646.1,
RC ECO:0000313|Proteomes:UP000281351};
RA Coil D.A., Jospin G., Darling A.E., Wallis C., Davis I.J., Harris S.,
RA Eisen J.A., Holcombe L.J., O'Flynn C.;
RT "Genomes From Bacteria Associated with the Canine Oral Cavity: a Test Case
RT for Automated Genome-Based Taxonomic Assignment.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in initiation and elongation during chromosome
CC replication; it exhibits DNA-dependent ATPase activity.
CC {ECO:0000256|ARBA:ARBA00002835}.
CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC {ECO:0000256|ARBA:ARBA00008428}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRD61646.1}.
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DR EMBL; RQYM01000002; RRD61646.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P1XUE2; -.
DR Proteomes; UP000281351; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00984; DnaB_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF03796; DnaB_C; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000313|EMBL:RRD61646.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000281351}.
FT DOMAIN 167..423
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
SQ SEQUENCE 438 AA; 47656 MW; 645B40189708117D CRC64;
MELPANYEAE RSVLGGLLLD PSYLNDVAAV IDDPAAFYDP KHEAIYRAIL QIVATGGRPD
AVTVTDFLTK SGELGKWQRP TICHELTADV VSPVLAVAHA SVIADAAIRR RLAIAGQAIA
ADAVAGIGRP DELVEKARKL VDESSHRVVL DTGYLFGAVD EIVHELQQGE AQVTRTGWNA
LNGLIGGLRP GALYIVGARP GVGKTVVGLN LAVKFAGLGS VGFVSLEMSR SELVKRAISA
EAGVKLSALI DGRTSIVDME MINSVKSVVD SWRLSILDNA ESLSQILLYA RTLHRKGDLK
LLVVDYLQLM RGDRKAESRQ QEVSEFSRAL KLLAKELQIP VVALSQLNRE SANRKNNEPL
ISDLRESGSL EQDADVVILL HREKTKARRL KMIVAKNRQG RQGEVTLNFE GEFCRIVDKP
FDPLGVFTVA EDKESTDV
//
