ID A0A3P2A8A0_9NEIS Unreviewed; 251 AA.
AC A0A3P2A8A0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=L-lactate dehydrogenase {ECO:0000313|EMBL:RRD91036.1};
DE Flags: Fragment;
GN ORFNames=EII21_03565 {ECO:0000313|EMBL:RRD91036.1};
OS Conchiformibius steedae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Conchiformibius.
OX NCBI_TaxID=153493 {ECO:0000313|EMBL:RRD91036.1, ECO:0000313|Proteomes:UP000269923};
RN [1] {ECO:0000313|EMBL:RRD91036.1, ECO:0000313|Proteomes:UP000269923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COT-280 {ECO:0000313|EMBL:RRD91036.1,
RC ECO:0000313|Proteomes:UP000269923};
RA Coil D.A., Jospin G., Darling A.E., Wallis C., Davis I.J., Harris S.,
RA Eisen J.A., Holcombe L.J., O'Flynn C.;
RT "Genomes From Bacteria Associated with the Canine Oral Cavity: a Test Case
RT for Automated Genome-Based Taxonomic Assignment.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- SIMILARITY: Belongs to the FMN-dependent alpha-hydroxy acid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00024042}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRD91036.1}.
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DR EMBL; RQYC01000003; RRD91036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P2A8A0; -.
DR STRING; 1121352.GCA_000620925_00775; -.
DR OrthoDB; 9770452at2; -.
DR Proteomes; UP000269923; Unassembled WGS sequence.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02809; alpha_hydroxyacid_oxid_FMN; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012133; Alpha-hydoxy_acid_DH_FMN.
DR InterPro; IPR000262; FMN-dep_DH.
DR InterPro; IPR037396; FMN_HAD.
DR InterPro; IPR008259; FMN_hydac_DH_AS.
DR PANTHER; PTHR10578:SF107; FMN HYDROXY ACID DEHYDROGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10578; S -2-HYDROXY-ACID OXIDASE-RELATED; 1.
DR Pfam; PF01070; FMN_dh; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR PROSITE; PS00557; FMN_HYDROXY_ACID_DH_1; 1.
DR PROSITE; PS51349; FMN_HYDROXY_ACID_DH_2; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000269923}.
FT DOMAIN 1..215
FT /note="FMN hydroxy acid dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51349"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RRD91036.1"
SQ SEQUENCE 251 AA; 27894 MW; AC83A3A76E5E65C4 CRC64;
KDIKNGLSAP PKPTLPNLLN LALKPEWCLK MLNTERHTFR NIVGHAQNVG DLSSLSSWTA
EQFDPSLSWD DVARIKDLWG GKLIIKGIMD PEDAEMAVKH GADAIVVSNH GGRQLDGALS
SILALPDIVS AVSGQTEIWL DSGIRSGQDI LKAWALGARG VMIGRAFLYG LGAYGQEGVT
RALEILYKEM DVTMAFTGHR DIQNVGREIL IKGTYPISEY ERTESELQKR RRIYDELYGW
PRASLRFGTM W
//
