ID A0A3P2AE23_9BACE Unreviewed; 667 AA.
AC A0A3P2AE23;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=RecQ family ATP-dependent DNA helicase {ECO:0000313|EMBL:RRD93338.1};
GN ORFNames=EII33_00355 {ECO:0000313|EMBL:RRD93338.1};
OS Bacteroides heparinolyticus.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=28113 {ECO:0000313|EMBL:RRD93338.1, ECO:0000313|Proteomes:UP000279562};
RN [1] {ECO:0000313|EMBL:RRD93338.1, ECO:0000313|Proteomes:UP000279562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OH1047_COT-310 {ECO:0000313|EMBL:RRD93338.1,
RC ECO:0000313|Proteomes:UP000279562};
RA Coil D.A., Jospin G., Darling A.E., Wallis C., Davis I.J., Harris S.,
RA Eisen J.A., Holcombe L.J., O'Flynn C.;
RT "Genomes From Bacteria Associated with the Canine Oral Cavity: a Test Case
RT for Automated Genome-Based Taxonomic Assignment.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRD93338.1}.
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DR EMBL; RQYF01000001; RRD93338.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P2AE23; -.
DR Proteomes; UP000279562; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:RRD93338.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000279562}.
FT DOMAIN 58..226
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 250..396
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 76736 MW; 3CEC70782BFFDF4C CRC64;
MNKSNFASRS LWEKRQEEVS SPPPCGGGEQ KEEASEPRFL LRQYWGYTSF RGIQEDIINS
ILAGKDTLGL MPTGGGKSIT FQVPALAQEG LCLVITPLIA LMKDQVQNLK KRGIKALAIY
SGMSRQEIIV ALENCIFGNF KFLYISPERL DTDIFRSKVQ KMKISMITVD ESHCISQWGY
DFRPAYLKIA EIRKLLPGIP VLALTATATP EVIKDIQKRL NFREENVFRM SFERQNLAYI
VRKTENKTGE LLHILRRMSG SAIIYVRNRR RTKEITELLH NEHITADFYH AGLDDATKDI
RQQRWQTGES RVMVATNAFG MGIDKPDVRI VVHMDLPDSI EAYFQEAGRA GRDGEKAYAV
ILYAKSDHAT LHKRIPDSFP EKKYIKDVYE HLQYYYQMAM GDGQGCVREF NIEDFCRKFK
YFPVPVDSAL KILTQAGYLE YTDEQDNASR LLFTIRRDEL YKLKEMDEET DKLIQIILRS
YTGIFTDYAF INEDSLATRS GLMRRQVYEL LIHLAKLRIV SYIPRKKTPY IIYARERVEK
HHLQIPPSVY EERKARYEKR IAAMLDYAGN ATTCRSRMLL RYFGEKNEHN CGQCDTCISL
KKEGGHKDGL AKELVEDVLR ALSEQTMTPA ALSERLSTDK ETLTRVLHGL LDEGRVIAVN
GMLEVKK
//
