ID   A0A3P3VL53_9GAMM        Unreviewed;       574 AA.
AC   A0A3P3VL53;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Chloride channel protein {ECO:0000313|EMBL:RRJ83455.1};
GN   ORFNames=D0544_16710 {ECO:0000313|EMBL:RRJ83455.1};
OS   Aestuariirhabdus litorea.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Aestuariirhabdaceae; Aestuariirhabdus.
OX   NCBI_TaxID=2528527 {ECO:0000313|EMBL:RRJ83455.1, ECO:0000313|Proteomes:UP000280792};
RN   [1] {ECO:0000313|EMBL:RRJ83455.1, ECO:0000313|Proteomes:UP000280792}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GTF-13 {ECO:0000313|EMBL:RRJ83455.1,
RC   ECO:0000313|Proteomes:UP000280792};
RA   Khan S.A.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:RRJ83455.1, ECO:0000313|Proteomes:UP000280792}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GTF-13 {ECO:0000313|EMBL:RRJ83455.1,
RC   ECO:0000313|Proteomes:UP000280792};
RA   Shieh W.Y.;
RT   "Simiduia agarivorans gen. nov., sp. nov., a marine, agarolytic bacterium
RT   isolated from shallow coastal water from Keelung, Taiwan.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RRJ83455.1}.
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DR   EMBL; QWEZ01000002; RRJ83455.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P3VL53; -.
DR   Proteomes; UP000280792; Unassembled WGS sequence.
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   CDD; cd00400; Voltage_gated_ClC; 1.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
DR   PROSITE; PS51371; CBS; 1.
PE   4: Predicted;
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Chloride {ECO:0000256|ARBA:ARBA00023214};
KW   Chloride channel {ECO:0000256|ARBA:ARBA00023173};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023173};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000280792};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023173}.
FT   TRANSMEM        26..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        241..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        271..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        312..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        401..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          519..574
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
SQ   SEQUENCE   574 AA;  61663 MW;  B6D2FF87BE2F7BAC CRC64;
     MRRPSPPQIM NQFRLRLANA EAVPQLALLG ILSGLITGAV IILFRQLLGW MLGTGLPEGN
     DENFEGLADH WRLLLPIAGS LVLVLLFALI APRHRQTGIA HVIERMALHQ GHLPFKNMLV
     QFVGALIALA SGHSSGREGP AVHLGAAGSS GLGHWLRLPN NSVRTLVGCG SAAAISAAFN
     TPIAGVIFAM EVVMMEYTIS GFIPVILASV IAAFMTALVY GSEHAFVIPL IEMRTLLEFP
     LVILCGLAIG CLAASFIWLS KQINRRAPSP YWFRLPLAGV LTGLVALQFP QVMGIGYDTI
     SDILFNTVGL EFLLLLVLAK LLVSAAACGL GVPAGTIGPS LFLGACLGGA IGLISQILYS
     GPSSGSGFYA MLGMGAMMAA VLQAPLAALM AVMELTHNPN IILPAMLAVV IASLTSRYLL
     GQGSLFAELL GREMADPRSL LEQGLHREGV ANIMDGGLVH LPRQCPLALA QELLRDAHKW
     VVVVEEESPR WIFRADELRL QMTEPDRPEA LDLLSIPALR KDIAPISDQA TVQEALQALH
     DAGTEALYVR DRKSNRAIGI VTQEFIQQHY RLYQ
//