ID A0A3P3W1B3_9MICO Unreviewed; 475 AA.
AC A0A3P3W1B3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:RRJ88287.1};
DE EC=4.2.3.1 {ECO:0000313|EMBL:RRJ88287.1};
GN ORFNames=EG850_02265 {ECO:0000313|EMBL:RRJ88287.1};
OS Gulosibacter macacae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Gulosibacter.
OX NCBI_TaxID=2488791 {ECO:0000313|EMBL:RRJ88287.1, ECO:0000313|Proteomes:UP000274391};
RN [1] {ECO:0000313|EMBL:RRJ88287.1, ECO:0000313|Proteomes:UP000274391}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 102482-1 {ECO:0000313|EMBL:RRJ88287.1,
RC ECO:0000313|Proteomes:UP000274391};
RA Li G., Jiang Y.;
RT "YIM 102482-1 draft genome.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRJ88287.1}.
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DR EMBL; RQVS01000002; RRJ88287.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P3W1B3; -.
DR OrthoDB; 9778118at2; -.
DR Proteomes; UP000274391; Unassembled WGS sequence.
DR GO; GO:0004795; F:threonine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR42690; THREONINE SYNTHASE FAMILY MEMBER; 1.
DR PANTHER; PTHR42690:SF1; THREONINE SYNTHASE-LIKE 2; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:RRJ88287.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000274391}.
FT DOMAIN 2..79
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 107..351
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 113
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 475 AA; 52086 MW; F1A6F616A345DB5D CRC64;
MQFISTRGGT EPKDYCEVLL EGLAADGGLV VPEYLPEVSA ETFESWRALS YPELATEVIG
LFATDIPRDE LARMCASAYD ASRFPNRAIV PLRDIGAGMT LVGLSEGPTL AFKDMAMQFL
GEAIEYALGR EDRVLNVLGA TSGDTGSAAE HALHGRDRVS VFMLSPQGRM SPFQRAQMYS
LLDDNIHNIA IEGVFDDCQH LVKQLSEDLE FKNEFNLGAV NSINFGRISA QIVYYVWAWL
RASDGVDAAD RADFKVSFAV PSGNFGNILS GFYASKLGVP VERLVLASNE NNVLDEFFRT
GWYRPRSAAN TLATSSPSMD VSKASNLERF VFELVGRDPA RVAEAWRELA AQGAIDFTVE
QLRFADEFRI VSGTSTHADR LATIHEVAER EGVLIDPHTA DGVHVAADFV EEGVPMLVLE
TAKPEKFAAT MAEALGRELE PSAEHQELLD APQRVLNMPN DEDALRLFIA EHALS
//
