ID A0A3P3WC28_9FLAO Unreviewed; 444 AA.
AC A0A3P3WC28;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase MtaB {ECO:0000313|EMBL:RRJ92722.1};
GN Name=mtaB {ECO:0000313|EMBL:RRJ92722.1};
GN ORFNames=EG240_02745 {ECO:0000313|EMBL:RRJ92722.1};
OS Paenimyroides tangerinum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Paenimyroides.
OX NCBI_TaxID=2488728 {ECO:0000313|EMBL:RRJ92722.1, ECO:0000313|Proteomes:UP000275719};
RN [1] {ECO:0000313|EMBL:RRJ92722.1, ECO:0000313|Proteomes:UP000275719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 102701-2 {ECO:0000313|EMBL:RRJ92722.1,
RC ECO:0000313|Proteomes:UP000275719};
RA Li G., Jiang Y.;
RT "Flavobacterium sp. nov., YIM 102701-2 draft genome.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRJ92722.1}.
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DR EMBL; RQVQ01000004; RRJ92722.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P3WC28; -.
DR OrthoDB; 9805215at2; -.
DR Proteomes; UP000275719; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0035596; F:methylthiotransferase activity; IEA:InterPro.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR Gene3D; 3.40.50.12160; Methylthiotransferase, N-terminal domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR005839; Methylthiotransferase.
DR InterPro; IPR020612; Methylthiotransferase_CS.
DR InterPro; IPR013848; Methylthiotransferase_N.
DR InterPro; IPR038135; Methylthiotransferase_N_sf.
DR InterPro; IPR006467; MiaB-like_bact.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR NCBIfam; TIGR01579; MiaB-like-C; 1.
DR NCBIfam; TIGR00089; MiaB/RimO family radical SAM methylthiotransferase; 1.
DR PANTHER; PTHR11918; RADICAL SAM PROTEINS; 1.
DR PANTHER; PTHR11918:SF45; THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF00919; UPF0004; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01061; methylthiotransferase; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51449; MTTASE_N; 1.
DR PROSITE; PS01278; MTTASE_RADICAL; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000275719};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RRJ92722.1}.
FT DOMAIN 5..117
FT /note="MTTase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51449"
FT DOMAIN 140..374
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 444 AA; 50729 MW; 082326FFEF129F59 CRC64;
MENRKKVAFY TLGCKLNFSE TSTIARNFND EGFDRVDFEE VADIYVINTC SVTDNADKQF
KQIVKKALKI NDKAFVAAVG CYAQLKPEEL AAVDGVDLVL GATEKFKITD YINDLSKNDM
GEIHSCEIEE ADFYVGSYSI GDRTRAFLKV QDGCDYKCTY CTIPLARGIS RSDTMENVMQ
NAAEISAKGI KEIVLTGVNI GDYGKGEFGN KKHEHTFLEL VQALDTVEGI ERLRISSIEP
NLLKNETIDF VSKSKTFVPH FHIPLQSGSN EILKKMKRRY MRELYQDRVS KIREVMPDAC
IGVDVIVGFP GETDELFLET FNFLNDLDIS YLHVFTYSER DNTEAIDFEG VVPMNVRSKR
SKMLRGLSVK KRRHFYENQL NTKHTVLFES ENKEGYIHGF TENYVKVKTP WNPELVNTLH
EIELTKIDED GIVRFNFINE PVFS
//
