ID A0A3P3WCZ8_9FLAO Unreviewed; 635 AA.
AC A0A3P3WCZ8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acs {ECO:0000313|EMBL:RRJ91509.1};
GN ORFNames=EG240_05745 {ECO:0000313|EMBL:RRJ91509.1};
OS Paenimyroides tangerinum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Paenimyroides.
OX NCBI_TaxID=2488728 {ECO:0000313|EMBL:RRJ91509.1, ECO:0000313|Proteomes:UP000275719};
RN [1] {ECO:0000313|EMBL:RRJ91509.1, ECO:0000313|Proteomes:UP000275719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 102701-2 {ECO:0000313|EMBL:RRJ91509.1,
RC ECO:0000313|Proteomes:UP000275719};
RA Li G., Jiang Y.;
RT "Flavobacterium sp. nov., YIM 102701-2 draft genome.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRJ91509.1}.
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DR EMBL; RQVQ01000010; RRJ91509.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P3WCZ8; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000275719; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:RRJ91509.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000275719}.
FT DOMAIN 12..68
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 70..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 635 AA; 71785 MW; 907B171DA0621BC3 CRC64;
MSYYKIGDLE QYFKHYKKSV REPRKFWGKI AEENFVWYQA WDKVFDFDME KHDIKWFTDG
KLNIVKNCID RHLSKRGEKA ALIFEPNDIN EQAQVISYNE LYVRVAKMAN VLKSQGIEKG
DRVCIYLPMI PELAIAMLAC ARIGAIHSVI FAGFSAEAIK TRVEDCGAKM VITSDGGFRG
AKTIQLKNIV DDAIKDLSSV EKVLVVKRTN EAVQMKEGRD LWLAPLYEVA EESNVAQIMD
SEDPLFILYT SGSTGKPKGM VHTTAGYMIQ TAYTFNNVFD YKDDDIFWCT ADLGWITGHS
YILYGALLNG ATTVMFEGVP SYPNPSRFWD IIDKHKVTQF YTAPTAIRSL MTEDYSYITG
HDLSSLRILG SVGEPINEEA WHWFNDFVGK KRCPIVDTWW QTETGSILIS PLANVTPTKP
TYATLPMPGI QTVLMDELHN EITGNQVMGS LCIKFPWPSM ARTIWNDHER YVQTYFSDFP
GCYFTGDGAL RDEVGYYRIT GRTDDVVIVS GHNIGTAPIE DAINQHPAVA ESAVVGYNHD
IKGNGLYGFI TLKVEGTTRD RENVKKEINQ LITSHYGPIG KLDKIQFVEG LPKTRSGKIL
RRLLRSIATN RLDTFGDTST MINPEVVQGI IDERQ
//
