ID A0A3P4B2C1_9BURK Unreviewed; 462 AA.
AC A0A3P4B2C1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Putative cardiolipin synthase YwiE {ECO:0000313|EMBL:VCU69850.1};
DE EC=2.7.8.- {ECO:0000313|EMBL:VCU69850.1};
GN Name=ywiE_2 {ECO:0000313|EMBL:VCU69850.1};
GN ORFNames=PIGHUM_01915 {ECO:0000313|EMBL:VCU69850.1};
OS Pigmentiphaga humi.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Pigmentiphaga.
OX NCBI_TaxID=2478468 {ECO:0000313|EMBL:VCU69850.1, ECO:0000313|Proteomes:UP000277294};
RN [1] {ECO:0000313|EMBL:VCU69850.1, ECO:0000313|Proteomes:UP000277294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DnA1 {ECO:0000313|EMBL:VCU69850.1};
RA Criscuolo A.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UWPJ01000016; VCU69850.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P4B2C1; -.
DR OrthoDB; 9762009at2; -.
DR Proteomes; UP000277294; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR CDD; cd09110; PLDc_CLS_1; 1.
DR CDD; cd09159; PLDc_ybhO_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000277294};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:VCU69850.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..462
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018257410"
FT DOMAIN 187..214
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 375..402
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT REGION 215..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 50446 MW; 355FA8C003D616DD CRC64;
MPRCLSVLLY AACVALLAAC AHPLPEVQAG SEPRQAVRIS TASGWLTYRD SQRIIRKLGG
PGDAGDFLAH HLQVEEAVAG TPLVAGNQVQ LFSDGPSTYR AMEQAIAAAR RFIHLESYIF
EDDDVGNRMA ELLMARRAAG VAVAVMVDDV GTIAVPRELF DRMRGAGIEV VAFNPVNPLA
GRGTWSLNER SHRKILVVDG AVAFVGGINV SDVYSSRPVS GSSPGASGDR SNAPWRDTHI
SIRGPAVQAV ERVFLEGWRS QNGPELGDID FLPPQPRAGP HVVRILVNKP GAGDNHAIYL
TLLSAINSAQ RSIHITMAYF VPDPAFIEAL CEAARRGVDV VLLLPGFSDF SMVVYAGRSH
YEELLAAGVK IYERKDALLH AKTAVVDGVW STAGSSNLDW RSFTLNHEIN AVILGPGFGA
QMEALFESDR RASVQVDYER WKRRPVSRRF KEFVSRLLER WM
//
