ID   A0A3P4B928_9BURK        Unreviewed;       430 AA.
AC   A0A3P4B928;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Cytosine deaminase {ECO:0000313|EMBL:VCU72218.1};
DE            EC=3.5.4.1 {ECO:0000313|EMBL:VCU72218.1};
GN   Name=codA {ECO:0000313|EMBL:VCU72218.1};
GN   ORFNames=PIGHUM_04316 {ECO:0000313|EMBL:VCU72218.1};
OS   Pigmentiphaga humi.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Pigmentiphaga.
OX   NCBI_TaxID=2478468 {ECO:0000313|EMBL:VCU72218.1, ECO:0000313|Proteomes:UP000277294};
RN   [1] {ECO:0000313|EMBL:VCU72218.1, ECO:0000313|Proteomes:UP000277294}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DnA1 {ECO:0000313|EMBL:VCU72218.1};
RA   Criscuolo A.;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UWPJ01000039; VCU72218.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P4B928; -.
DR   OrthoDB; 9815027at2; -.
DR   Proteomes; UP000277294; Unassembled WGS sequence.
DR   GO; GO:0102480; F:5-fluorocytosine deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004131; F:cytosine deaminase activity; IEA:UniProtKB-EC.
DR   CDD; cd01293; Bact_CD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR013108; Amidohydro_3.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR32027; CYTOSINE DEAMINASE; 1.
DR   PANTHER; PTHR32027:SF0; CYTOSINE DEAMINASE; 1.
DR   Pfam; PF07969; Amidohydro_3; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:VCU72218.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277294}.
FT   DOMAIN          40..400
FT                   /note="Amidohydrolase 3"
FT                   /evidence="ECO:0000259|Pfam:PF07969"
SQ   SEQUENCE   430 AA;  46501 MW;  B87363E10D85FCA5 CRC64;
     MLDAILKDCS LPDGRTGIDI GIADGRIAAV QPQLQAQAAR VVDAAGQLVS PPFVDAHFHM
     DSTLSYGLPR VNGSGTLLEG ISLWGELKPL LSQEALVERA LTYCDWAVAK GLLAIRSHVD
     VCDPRLLAVE ALLHVRERVR PYLDLQLVAF PQDGVLRTPD ALANLKRALD MGVDVVGGIP
     HFERTMQDGA ESVRILCELA AQRGLRVDMH CDESDDPLSR HIETLAFHTQ RLGLQGRVAG
     SHLTSMHSMD NYYVSKLLPL IHEAGVAAIA NPLINITLQG RHDTYPKRRG MTRVPELLEA
     GVPVAFGHDC VMDPWYSLGS ADMLEVAHMG LHVAQMTGQT AMRACFTAVT DTPARILGLV
     DLGIAPGKRA DLVLLQARDP VEAIRLRATR LLVMRAGKVI ATKPPATTSL FVQGRPGVVT
     FQLPPLATAS
//