ID   A0A3P5WQE4_9RHOB        Unreviewed;       375 AA.
AC   A0A3P5WQE4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Lysine 6-dehydrogenase {ECO:0000313|EMBL:VDC17234.1};
DE            EC=1.4.1.18 {ECO:0000313|EMBL:VDC17234.1};
GN   Name=lysDH {ECO:0000313|EMBL:VDC17234.1};
GN   ORFNames=PARPLA_00574 {ECO:0000313|EMBL:VDC17234.1};
OS   Rhodobacteraceae bacterium THAF1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae.
OX   NCBI_TaxID=2483814 {ECO:0000313|EMBL:VDC17234.1, ECO:0000313|Proteomes:UP000275054};
RN   [1] {ECO:0000313|EMBL:VDC17234.1, ECO:0000313|Proteomes:UP000275054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATHAF1 {ECO:0000313|EMBL:VDC17234.1};
RA   Criscuolo A.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UXAS01000011; VDC17234.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P5WQE4; -.
DR   Proteomes; UP000275054; Unassembled WGS sequence.
DR   GO; GO:0050303; F:lysine 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:VDC17234.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275054}.
FT   DOMAIN          9..112
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          116..362
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   375 AA;  40852 MW;  19330E386A34857C CRC64;
     MTIHWCGTGL SAVPGLKRLL DAGRDLVVWN RTVETARAVA GPDADVRAFD LDALAAALQA
     GDVVVSMLPA AMHVALATRA IDAGAHFVSS SYIAPEMRAL DDAAHEAGVS VVNEIGLDPG
     IDHLFAHDLM ADYRASDAFD PANQLHFLSY CGGIPKVPNP FRYKFSWSPL GVLTALRSPS
     RSLRNGDVFD AARPWEALSR YDAPLPQPET FEVYPNRDSL PFMAEYGFDP AWDVRDFVRG
     TLRLDGWASA WGEVFERVET ADDATLRDMA RAFWRDNAYD AGEPDRVVMV VDLRAARDGA
     DVYHKTWVMD AWGDADGTAM ARLVSNPVAR AVEAVAAGDM PSGVQAAPSR PDQVAAFIDE
     VRSLAQHVER VDRLS
//