ID A0A3P5X0R7_9BACL Unreviewed; 668 AA.
AC A0A3P5X0R7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Beta-lactam-inducible penicillin-binding protein {ECO:0000313|EMBL:VDC24900.1};
GN Name=pbp {ECO:0000313|EMBL:VDC24900.1};
GN ORFNames=FILTAD_01120 {ECO:0000313|EMBL:VDC24900.1};
OS Filibacter tadaridae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Filibacter.
OX NCBI_TaxID=2483811 {ECO:0000313|EMBL:VDC24900.1, ECO:0000313|Proteomes:UP000270468};
RN [1] {ECO:0000313|EMBL:VDC24900.1, ECO:0000313|Proteomes:UP000270468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATB-66 {ECO:0000313|EMBL:VDC24900.1};
RA Criscuolo A.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; UXAV01000031; VDC24900.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P5X0R7; -.
DR OrthoDB; 9770103at2; -.
DR Proteomes; UP000270468; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR007887; MecA_N.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627:SF25; PENICILLIN-BINDING PROTEIN 3; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR Pfam; PF05223; MecA_N; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000270468};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..668
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018102032"
FT DOMAIN 25..148
FT /note="NTF2-like N-terminal transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF05223"
FT DOMAIN 156..318
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 356..664
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 668 AA; 74365 MW; 1741C180BF821442 CRC64;
MKKWRVLSIF LILIIALAAC SKKDTPEDRL ASYTKLWKDA EFTKMYEGYL SDASKDVFGP
DEYIDRTTKL YKDLAITDVQ IKFKNPDEDK KYKKEDQPEF PVQIKMETVA GPIEFEKKVM
MTYGKSGEEE NWFVEWDPSF NLPNLTMNDK VGVSKLPSKR GEILDRNGSP LAINGKGYEA
GIVPEKFNEE KDAERLAKIL NTTPDYIKKQ LNQSWVKPDQ FVPIKKVAST QNAIVEKMIE
VPGVTYTQVE MREYPYGESL SHLVGYIGRI NADELEKVKD KGYKETDLIG KRGLEQLLDE
QLRGEDGARI YIEKTNENAE KITIAEKTAV DGKSLSLTID ADLQQKTFKA MDGEAGTATA
IDPKTGEVLV LTSSPAFDPN EFVIGVSASH YDKLSKDPLQ PLLNRFAATY APGSAIKPIT
AAIGLEAGTI KPEKGYTIEG KRWKKDESWG NFGVTRVYTP PNPINLKKAI VHSDNIYFAM
EAIEMGKKTL IEGFKKFGFE KDIPFSYPLR ASQISNDVTI GTEAQLVDTS YGQGQMLMNI
VHLASSYSPL LTNGKMVKPV LFADETKSEI WKEGLISPEN AAILRADLRE VVTKGSGKDA
DIPSVKISGK TGTAELKSGQ DKRGKENGFF VGYQTDETAY IMAMMIESIE DNGGSGYVVK
KVAEVMAE
//
