ID A0A3P5X300_9BACL Unreviewed; 466 AA.
AC A0A3P5X300;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=L-cystine uptake protein TcyP {ECO:0000256|ARBA:ARBA00022031};
DE AltName: Full=Transporter of cystine TcyP {ECO:0000256|ARBA:ARBA00031293};
GN Name=tcyP {ECO:0000313|EMBL:VDC22389.1};
GN ORFNames=FILTAD_00735 {ECO:0000313|EMBL:VDC22389.1};
OS Filibacter tadaridae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Filibacter.
OX NCBI_TaxID=2483811 {ECO:0000313|EMBL:VDC22389.1, ECO:0000313|Proteomes:UP000270468};
RN [1] {ECO:0000313|EMBL:VDC22389.1, ECO:0000313|Proteomes:UP000270468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATB-66 {ECO:0000313|EMBL:VDC22389.1};
RA Criscuolo A.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UXAV01000021; VDC22389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P5X300; -.
DR OrthoDB; 7778689at2; -.
DR Proteomes; UP000270468; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF5; L-CYSTINE TRANSPORTER TCYP; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000270468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 466 AA; 49549 MW; 5CFFED58E88AF6AC CRC64;
METFHIILVI ALFLAMCAVL FYMQKKFVSF SKRVLLALVV GIVYGLALQF IYGQSSFIIS
ESAEWINIAG NGFITLLRML VMPLVFFAIL SAFTKSKLAN DFGKIGGLVI AMLAGTVAIA
AAVGIFSAGI FQLEGMEITQ GEAEMSAIAG HGDKLDTLNE MTIPGKIVSM LPSNIFSDLT
EARPTSVISV VIFASILGMA FMGVKRKEPE QAKLFASIVE AIFTVVMRVV TLILRLTPYG
ILALMVNKAA TSDLVAFWNL GKFIVASYLA IFIMFLVHLL LIRMVGLNPI TFIKKIMPVL
IFAFSSRSSA GTLPLNVSTQ KKSLGVSEGI ADISGAFGIT IGQNGCAGIY PAMLAIMVAP
TVGIDPFTPS FIAMLLVTVV IGSFGIAGVG GGATFAGLIV LSTMNLPVAI VGLLISIEPL
IDMARTALNV SGTMTTGVIT SKITKQLDEE IFNSKEEQVI GEVAQN
//
