ID A0A3P6ITX4_ENTVE Unreviewed; 443 AA.
AC A0A3P6ITX4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=EVEC_LOCUS6628 {ECO:0000313|EMBL:VDD91877.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|EMBL:VDD91877.1, ECO:0000313|Proteomes:UP000274131};
RN [1] {ECO:0000313|EMBL:VDD91877.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UXUI01008588; VDD91877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P6ITX4; -.
DR STRING; 51028.A0A3P6ITX4; -.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR032406; CLZ_dom.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638:SF5; CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF16526; CLZ; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 273..387
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 443 AA; 51605 MW; BAC8218336ED1F38 CRC64;
MIAVFPTEIL YVFNSNLVLV RLNRLAKVYR VRQFVDLTQI RTGFPSVFRT LKLAVYCYLI
FHWNGCLYFH YSVYYNIKDG TPLDWKFSYG KIMNPLLVEC KSRIHNKARC IFIRSLIIVR
QFFRTKVIEF GKFTRKYLQS FYWSALTLIT LGEQPPPSAT FQNQFEIMDT VIGLVIFAVI
ISDISNMVND LNASKSEFEF ELDGCKLFMY NRKVLHVLQK RVIDWFGYMK NEGILRNDEE
VSNFLPRRLF VELISSIHIQ TLLQSDLFQI DFLQKIILKL QLRIYSPMDY VCEKGDVGKE
MFIIKEGQVQ VVSDDGTKVF ATLSKGSVFG GLSILNIPGN KNGNKRTASI RSVGYTDVYV
LTKDDLWEIL QDYPALKNKL LERGRKVLEK DNLLENTDEE PELHEYATLD EKLEFITAQL
NNYDVKLKNL YDDFSVCFAV LNS
//
