ID A0A3P6T194_LITSI Unreviewed; 312 AA.
AC A0A3P6T194;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 03-MAY-2023, entry version 14.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:VDK74165.1};
GN ORFNames=NLS_LOCUS2371 {ECO:0000313|EMBL:VDK74165.1};
OS Litomosoides sigmodontis (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK74165.1, ECO:0000313|Proteomes:UP000277928};
RN [1] {ECO:0000313|EMBL:VDK74165.1, ECO:0000313|Proteomes:UP000277928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the processing of the 27S pre-rRNA.
CC {ECO:0000256|ARBA:ARBA00003387}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the EBP2 family.
CC {ECO:0000256|ARBA:ARBA00007336}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UYRX01000107; VDK74165.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P6T194; -.
DR STRING; 42156.A0A3P6T194; -.
DR Proteomes; UP000277928; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR008610; Ebp2.
DR PANTHER; PTHR13028; RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR13028:SF0; RRNA-PROCESSING PROTEIN EBP2-RELATED; 1.
DR Pfam; PF05890; Ebp2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT REGION 235..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..279
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 36509 MW; A81E2E0F2C63CD1A CRC64;
MVDFLKECLC QMRREEMDTT DGDVDTQIFS AIETEEESSD SDRELQIALN EGLLRTDRLN
YVVEKKRPII NKKAEMEGKV EELKKNLTWL ETLDVTVNND QVGNRVLNDD FEREIIFYKQ
AEKAVQIAVL KLREMGVKIF RPTDYYAEMV KSDQHMQKIR QRMAEIEEGK QKLEAIRRIR
QEKKFAAKVQ KKVMERKQNE KKVLAEAVKK HQKGVKSHLD AILNNAKKLQ DDEVKVKRTE
KERMRGSNNK SRSRRMARDK KYGFGGQKKR SKKNDKNSFE EIATPGSLAR RVKGSRFGVS
VRRSGAKQRK KR
//
