ID   A0A3P6TA33_LITSI        Unreviewed;       928 AA.
AC   A0A3P6TA33;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE   AltName: Full=Exportin(tRNA) {ECO:0000256|ARBA:ARBA00029784, ECO:0000256|RuleBase:RU366037};
DE   AltName: Full=tRNA exportin {ECO:0000256|ARBA:ARBA00032199, ECO:0000256|RuleBase:RU366037};
GN   ORFNames=NLS_LOCUS5501 {ECO:0000313|EMBL:VDK81907.1};
OS   Litomosoides sigmodontis (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX   NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK81907.1, ECO:0000313|Proteomes:UP000277928};
RN   [1] {ECO:0000313|EMBL:VDK81907.1, ECO:0000313|Proteomes:UP000277928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC       translocation across the nuclear pore complex.
CC       {ECO:0000256|RuleBase:RU366037}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC       ECO:0000256|RuleBase:RU366037}. Nucleus
CC       {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC       the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|RuleBase:RU366037}.
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DR   EMBL; UYRX01000417; VDK81907.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P6TA33; -.
DR   STRING; 42156.A0A3P6TA33; -.
DR   Proteomes; UP000277928; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR045546; Exportin-T_C.
DR   InterPro; IPR040017; XPOT.
DR   PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR   PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR   Pfam; PF19282; Exportin-T; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW   Transport {ECO:0000256|RuleBase:RU366037};
KW   tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW   ECO:0000256|RuleBase:RU366037}.
FT   DOMAIN          107..180
FT                   /note="Exportin-1/Importin-beta-like"
FT                   /evidence="ECO:0000259|Pfam:PF08389"
FT   DOMAIN          300..830
FT                   /note="Exportin-T C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19282"
SQ   SEQUENCE   928 AA;  106466 MW;  BDFEB31DF1CD03A1 CRC64;
     MKGVLFEGAT LVDSVALTIM VSIASLANTA QHHTIFECIE KLKNDCDGWK NCIEKIINGC
     DPEEHFMLLQ VIETYLTVRY ADSDQDHNII RRWMCGWLQH LSSRSQPSYL VNKMAQLFAL
     VFAADFPKRW PNFMEEVFFQ QMVSSPEITV FFLRTLIAID CEVVDREIRR TKQAENSDLK
     TRKLCLDVIA CYIDWIDLEL VVNSTTIPFI INCLKNEYTC ESAVSAISAM VMKGMDAEKK
     LLLTVSLCTV LRDNGSLDLK KNDVDDVLRT GPLINSLGCA LIDCHACFSK VGDMEKAMEC
     EALLRQQAEI ALLCFSYEDI DASETVIEFL RRYVYILKTQ EFEKRHDFTS RMICIAMDRY
     KAGSVDLNST DGEVVAEFMA YRRQLRNMLS AIGNFEPEEI LTKLELSVRN VCENWKQCHV
     NVVEATLALV YDLPDFVHTN FGNNSSVICD RAKKMVLKIL QSTINHCGLP CINTLFFEIA
     CHCERVLQSS TGPLPMILEA FLDTRGLRQV SLQSRSRIIY LFCRFVKAHK LFIGSQAENV
     LAKLESFFTV TSEEDYQLSK EDQMYLYEST SVLIVHSNLF VERKQECIKA LGLSLLQKFS
     RITERLSRTK NVEEVHQLYQ RYADVIGYSA RVTKAFTNNY TMQCCQCTII FIELMEVFLD
     KITPDNVEGL DALRQYLHRM VTCLDSEILV MLPAICAKYL DVGSNLKVAH DFLILLQQIF
     GKFKKRLLET GLDIPALFDI LWSAQRIPFD ISNENGDRDI IYYNRAYLQT ILSILTNDLI
     VVLTDGTKFL HKVADSLVSF MDLNDIPTQR LTFQIINKLF RRLSNDGSAI DFLWEKAVSG
     AFLTPLNGHH DLADAQCVLL QHEIYVCLQT LRSYSFERFD RHLQLFLPID IARNFCQCIC
     SYKGKQLENA LDMQYVQLRL MKAERVAP
//