ID A0A3P6TGS6_LITSI Unreviewed; 331 AA.
AC A0A3P6TGS6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=Ephrin RBD domain-containing protein {ECO:0000259|PROSITE:PS51551};
GN ORFNames=NLS_LOCUS5814 {ECO:0000313|EMBL:VDK82559.1};
OS Litomosoides sigmodontis (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK82559.1, ECO:0000313|Proteomes:UP000277928};
RN [1] {ECO:0000313|EMBL:VDK82559.1, ECO:0000313|Proteomes:UP000277928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ephrin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00884, ECO:0000256|RuleBase:RU004375}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00884}.
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DR EMBL; UYRX01000462; VDK82559.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P6TGS6; -.
DR STRING; 42156.A0A3P6TGS6; -.
DR Proteomes; UP000277928; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd02675; Ephrin_ectodomain; 1.
DR Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 1.
DR InterPro; IPR008972; Cupredoxin.
DR InterPro; IPR031328; Ephrin.
DR InterPro; IPR001799; Ephrin_RBD.
DR PANTHER; PTHR11304; EPHRIN; 1.
DR PANTHER; PTHR11304:SF44; EPHRIN-4; 1.
DR Pfam; PF00812; Ephrin; 1.
DR PRINTS; PR01347; EPHRIN.
DR SUPFAM; SSF49503; Cupredoxins; 1.
DR PROSITE; PS51551; EPHRIN_RBD_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00884}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|RuleBase:RU004375};
KW Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..141
FT /note="Ephrin RBD"
FT /evidence="ECO:0000259|PROSITE:PS51551"
FT REGION 150..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 36..76
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00884"
SQ SEQUENCE 331 AA; 37341 MW; 6574409829C7772F CRC64;
MCCRFTDRSL FPQDAEIGAG AAYIEVDAMD SMEIVCPTYS VHDNANTYEQ LIVHQVSDLS
FMSCELDSRS QAFLVCDSPL ATTSISHKIV FRQFSPLPNG FEYQPGRSYY LITTSNGSTE
GMNNTRLGLC VTANMRLRID VRPLNDNFYP SSDEGMDLKS ASESSEAERA EREEWSRSRR
VRPSTNDKVK TEQDIDSLNN ESQKFAEKHG FDLTRLEYVR QLAIDGVEGD FSFRELENDS
VKASVDPSKT TFAGGPGRPR FSNTLSNREL YHSTSRQAQR WISKEIQSRS GASPDVFPEQ
DINGGGARFR RMEAKYVIIN VLLLLLWNLG K
//
