ID A0A3P6TQ84_LITSI Unreviewed; 668 AA.
AC A0A3P6TQ84;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
GN ORFNames=NLS_LOCUS451 {ECO:0000313|EMBL:VDK68504.1};
OS Litomosoides sigmodontis (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK68504.1, ECO:0000313|Proteomes:UP000277928};
RN [1] {ECO:0000313|EMBL:VDK68504.1, ECO:0000313|Proteomes:UP000277928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; UYRX01000011; VDK68504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P6TQ84; -.
DR STRING; 42156.A0A3P6TQ84; -.
DR Proteomes; UP000277928; Unassembled WGS sequence.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR CDD; cd11238; Sema_2A; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF139; SEMAPHORIN-2A; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..668
FT /note="Sema domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017946636"
FT DOMAIN 13..480
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 668 AA; 74699 MW; FD74599CFF395BCB CRC64;
MMSSQLLSVD ILIFALHFLE AFTLSTIFPE NVFTVGRLAY RRLLLDPQSA SLYVGANGHL
FRLWAYNINA TASTDGLYAH AELPVSRSDA EECRQAGHVE CVNGVRLMFL KEGHQALLVC
SSNAMKPQLR ELDALSLEER SSPENVIGVC SAHVDLNTTA VLVEWGNPDD IPAIYSGIRT
GLILDNNLIY RPPLIKNSKE VYSSMRTIYT DSKWLYEPDF VASFDIDKYV YFFFREVAIE
RGNCERVVFS RVARICKKDI GGKNVLRQVW TTFVKARLNC STSSKFPVYF NELQSLQIVD
GGSDSLFYAT LTTPEISLGG SAVCVFSLSN INQLLDHGYF LEQTSSDGGW ITTPSKNVPE
HRPGTCATNS ASVPDSSLHF ARSHLLMADA VSADLPLLVL RDELLTHIAV DTVEDINVIF
VYSHSSQKLH KIAHWFGADK NSKLLATYAL KNNGVVFAMT LLPGEFVYLS GEDNVAQYLL
SQCSLYTTCA QCAVDPYCSW NTARGLCYKR EQAHLSTAGW VSSSPKDVNK CLGHVKRMTT
NAYVGDTLHL TCVAQSKWIF NTESVSPSSK RQLTTEGGLV IFNVSGTDSG IYECNVDEQA
VMIYEITVDD AECVQPTSIA QFKSKYREWC QKFAKYKHST EKWQLWYDRN AANCPKQRFT
DFNHVIIE
//
