ID A0A3P6TUZ1_LITSI Unreviewed; 1103 AA.
AC A0A3P6TUZ1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
DE Flags: Fragment;
GN ORFNames=NLS_LOCUS9237 {ECO:0000313|EMBL:VDK89697.1};
OS Litomosoides sigmodontis (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK89697.1, ECO:0000313|Proteomes:UP000277928};
RN [1] {ECO:0000313|EMBL:VDK89697.1, ECO:0000313|Proteomes:UP000277928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR EMBL; UYRX01001448; VDK89697.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P6TUZ1; -.
DR STRING; 42156.A0A3P6TUZ1; -.
DR Proteomes; UP000277928; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR Gene3D; 3.10.250.10; SRCR-like domain; 2.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR47653:SF1; DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN; 1.
DR PANTHER; PTHR47653; PROTEIN BARK BEETLE; 1.
DR Pfam; PF00530; SRCR; 2.
DR SMART; SM00710; PbH1; 9.
DR SMART; SM00202; SR; 2.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR SUPFAM; SSF56487; SRCR-like; 2.
DR PROSITE; PS50287; SRCR_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000277928}.
FT DOMAIN 79..191
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 967..1089
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 154..164
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1055..1065
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:VDK89697.1"
SQ SEQUENCE 1103 AA; 124137 MW; 4D2BFC4295F64966 CRC64;
VYSNNVTLYY RNSPYRIQTD LTIGTKAVLT IETGVKIYFD TGVGIKIKGA MWAVGNEFAR
IQMLPYQRVV SYNSEMPQFR LIDGSSVRQG RLQIKFQNRW RSICTKLTNW TSVDVSTACR
SMGFNDGGIF FIGFWKWYQR NNDTYPFVMP SPKCQPNVLS LWECEGFRNP DMIPLSENLC
HGEDDIGIRC WGEPIFLGWQ GHWKGLQFFS SSLKYVNSDP DMVALHQESV SRLEFVDLLY
AGYDRSTRNT TAAIWVEGIP PIMNGLRIER SCGGAVHLVR PAAPVVIANS TIRNNRGHGI
AVMDTIDGRV FINMTTISGN YGDGVHYREA YDQSSYLAMF GKHSVARTAG FLDDNKKPRL
DMCMEHKIPH TFFFPHLIEV KLTNGTIISL PPKLLYTYSI QFMSVRNEND KNSDSETRLI
ICDANANFDG CDGERYRIPI LNRILPQTVS FRSSGQPVYL SLEHTTSGLS GRVAGDINLT
FLIHASVTDN TFYGLNITHT LIANNIGNGI LAQDIRERTV LTNVTVVENE GQAGLLVRDG
AADLWINASR ISNNLGDGIN VSYAGGSITI NGTIIGGNKW RGCAFHQNTS SPYLPLHQEI
VIKGRPSNNI LYLRTQIVDN AWGGILIGNF CIPSWRNIQP KVLISWIELV GNRYHASVEI
FACQKDGVAN TVVDFTGNRI EAGLGVGFRM EPAVNTIAII SSNQFIANND TALIIRNSRF
PQLHNLPAQV IISKNSFKFN TGQSIIAVGM VEGSQNQNLT FNQQNEVREN RVVNPFPYLN
PRFTPYAALV VSSSNVVINR NCFKNPQATY EIGTELGEHA KWIDARENNW GYPRPELFMH
RIFDQFNRYT LATIEVNPFA AVCNQRRPHI TAVQQYYRSF RKDSEPYILG GTIWENQDLG
KGLYTVVDDL NIVPGARLTL SPNTILQFNN GLGMLVQGEL VRTELHSSDE MVKFTSTPFV
LPRPLNIRLV DENDNIDVSD CRYIDIELLY TVLAGRLEVY VNNQWGTVCN RSWTKELALL
ACNQLGLIMD PEYPENWQVF PPPGELPLVM DNIRCEEREY DITNCRHDGI SHSIIASCAS
TDVVGLFIFE IIGQIRNEVQ TNL
//
