ID   A0A3P6TXL8_LITSI        Unreviewed;      2468 AA.
AC   A0A3P6TXL8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   03-MAY-2023, entry version 14.
DE   RecName: Full=Dopey N-terminal domain-containing protein {ECO:0000259|Pfam:PF04118};
GN   ORFNames=NLS_LOCUS7516 {ECO:0000313|EMBL:VDK86235.1};
OS   Litomosoides sigmodontis (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX   NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK86235.1, ECO:0000313|Proteomes:UP000277928};
RN   [1] {ECO:0000313|EMBL:VDK86235.1, ECO:0000313|Proteomes:UP000277928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the dopey family.
CC       {ECO:0000256|ARBA:ARBA00008395}.
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DR   EMBL; UYRX01000788; VDK86235.1; -; Genomic_DNA.
DR   STRING; 42156.A0A3P6TXL8; -.
DR   Proteomes; UP000277928; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0006895; P:Golgi to endosome transport; IEA:InterPro.
DR   InterPro; IPR040314; DOP1.
DR   InterPro; IPR007249; Dopey_N.
DR   PANTHER; PTHR14042; DOPEY-RELATED; 1.
DR   PANTHER; PTHR14042:SF24; PROTEIN DOPEY-1 HOMOLOG; 1.
DR   Pfam; PF04118; Dopey_N; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          25..308
FT                   /note="Dopey N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04118"
FT   REGION          1141..1187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2033..2071
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1150..1174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2033..2062
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2468 AA;  277848 MW;  7E82E3D5DAE5CAFA CRC64;
     MSSVLVGYTD AAANAAQAAS LINNSKYRAY VTAVDKALKA FEATNEWADL ISALAKLSRV
     FHANAKFGDI PKPVTVAKRL SQCLHPALPH GVHLKALETY RQLFDILGRK DLPRLLYLFA
     VGLFPLMDHC GIKVKSELLN IFEQYLLPLG VELKPALPGF IAGVLLGLEE GTEFYDRSFS
     LLDRVQESVG SESYFACLWE AVLGSPSVRL PALMYVNAKF CRRKSIHDQE YIMGNNIDHM
     IAALCAAADD DGSTLVQRHL LDFLSSAFPL NSDHLVREDF VQLLRRCLFL VLRRDMSLNR
     RLYQWLLNRV GDSAVTGLPV AGVDEQLDTT FFITYALPIA RKAIEEYLKL DTVQITSGLA
     SWDGTKEHQI QYTEVRVARL LLYFLDRPEL GSLLLEETLL ILLEAAAKND TRLEAILIEK
     EEILSRRKGL STSVKTISEQ NRRFSITSKS SVGSRQSRLS ILSVSDETSA EQIKRLEEFG
     KTINLLMNSL DIGLIQQKQK EQQNGTVDPY LLTNEVKMLK EEEEQRTTHE LANFPQIVLF
     CLNTIELDSH VDIRERYLPQ LLSSILTTVA ERNVTSIDGQ LLVRLLIVAN VILSEINQSA
     VVMEAGVATR KHGETYETDQ PDTMEKSSTQ AGAIKEQWRV EHCLSSCQRL LAQICDWYGN
     ERDTERLQAF YAISTLTREF ADFPLYDLDT QDMKSVEYLK RHESDNYPVW LSALLSILSL
     DEWDASINSN ADDLTPEIRV TDMFARADAL DLITYVYVRS ISVAEQHAAM LRRQRKDNKE
     RTIILLKPLI SEADLKRLDD DEIFKKAGKI LWSYLDQSDK AYCHSTVARL LCLFHSRKPS
     EPSSDVEDLI VSNLTSTNRE LSCCAAKKFR TLWMLNRPSA AVELYLGLSS KPFNRVVMLL
     LGFLCDDTTA GYDKAELKNI SACWFNDCAQ HSDLPYILQM WATMLLNPST SRASIQYLDM
     HRRMNKEKFA YIPSGICAVT LLTNSGHQSL HHLCEDVSAT DSHEAKRHLI EASAAFEKLR
     TGEHPTWLTE LRNNLLQGND DNNTMDLNVA SEAQRTHRRT VSDIPMFDDD NDSIETASLD
     SLDHEVVETL QYILDCICAQ EESEMEIQAC FAGERLCSHV QITLTSDAHD TETEISEKEG
     LFGGTERESQ KIAGESQSSP VGSAWKSVEN GPSVSENFKR PRGHRRQDSF QESIFTMSAQ
     ELKLFDTSEL PRLEATGDEV QPLCHELHAH MLLYVESGQT VDLARSEKIF RMLIALMRTK
     LSFLTRRLII NCMVSSGTAS FPKSLSGVAS GQLMDLVSRH IRSILGQDFW ASESDSASGT
     DTLKYKHYTF LELFMTASFF YVFFGSFLTD RISLHFLRSY FVNSPTANVS SLDLRNAWKC
     KMAVLDFLTE LVRGLIAIIQ ENHSRALTIY IHGLLQRSKL QKCLLHSLLT SVHNVRQHNN
     VEIIPLSVDI LEFNDGTATS SNFCDLIVGY QSSLLELTAT VIQLELNNGG LGKLTINHQI
     YNSPQHRATL REPYVSMVEL RMFLLTVLNA LKKHSTEQEQ WLTFAVRILP FLDRSLSTFS
     VHVVEQLCRN LESAVNAAYF PTDDKIHKIS SAESVPIRSI GFIHDKQTYP TNYAIGAIRF
     WLGRGAQRLL KCELFGSDKI LETLNMFFHY CLIDNTSQAS ATLTLASVQQ TSQVVAVNNP
     SLASSVMNAI PGTRGATELI SNLVKVFSFS DSTNESSNAA LSKFTDLTAD DVRKQARSDV
     LNAFPHALAT ICDVWTQLRK GEPNLPIGNP VIIRQLILEL LSPIVQRHQQ AFLSSLALVW
     MTRSSLTSQK QLTTRAESDQ PSFDYSPAQL DIADLLLNIK ILPFENLIST VAEAMKESAW
     KIAKSGISLE KNWLQQSAFP TELALLEMLH GCVRTTPPTA LYNCWPSLQA LFVESPVMSL
     PPKAVFIHIL VDFVHLATNS AVADDKQVSR AVQDACQKLT EAMNIIVGWQ LEQTTWLKRT
     LVVKHDSSAQ KSQETSPVVE FSTAPTSLAA SENSSLRGST SSLVPPRIPT FDTSTQISIS
     SQGASSLTAD RRSVSNMRSN LKDPNSLKRD PTHSTQALFL LAEHLAELID SICKSEDKER
     LLPLLHAVWS NTLPYLKAKN ARNARFFLAG SQLLASMSTF NYMRSVWRKA TLDLLLDPAF
     FKMDIQSLKH WLVITDHLMT YDKTSFKELL GRISTAQNSA LSSLITSKEV EYEMRAQALK
     RLAFIILSSE LGQYQSQLPD IQERLSDNLR LSQVPNVHAQ VFLCYRVLLI RQKPQHLVSM
     WPSMVTELVQ YTVHVLLQIE QQLSGTTNVS DDLKCDRNDQ WMQLYLAACK LLETLCTLPA
     GYLAQFQMCH WAFVNSVATS NIGSFVPFAS RIDHLLRNKY GQLSAHCRKV MSASLVNVKT
     LTSFSELRSF FLALATQNEM RSLTMQFAFD KEDQLRDAHF LNGSLPYKAA INRLEHALYV
     DFAEHWQL
//