ID A0A3P6U253_LITSI Unreviewed; 571 AA.
AC A0A3P6U253;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Doublecortin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NLS_LOCUS1874 {ECO:0000313|EMBL:VDK72718.1};
OS Litomosoides sigmodontis (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK72718.1, ECO:0000313|Proteomes:UP000277928};
RN [1] {ECO:0000313|EMBL:VDK72718.1, ECO:0000313|Proteomes:UP000277928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; UYRX01000076; VDK72718.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P6U253; -.
DR STRING; 42156.A0A3P6U253; -.
DR Proteomes; UP000277928; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR Gene3D; 3.10.20.230; Doublecortin domain; 2.
DR InterPro; IPR003533; Doublecortin_dom.
DR InterPro; IPR036572; Doublecortin_dom_sf.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR45901:SF6; LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45901; PROTEIN CBG12474; 1.
DR Pfam; PF03607; DCX; 1.
DR Pfam; PF01477; PLAT; 1.
DR SMART; SM00537; DCX; 1.
DR SUPFAM; SSF89837; Doublecortin (DC); 2.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR PROSITE; PS50309; DC; 2.
DR PROSITE; PS50095; PLAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000277928}.
FT DOMAIN 65..147
FT /note="Doublecortin"
FT /evidence="ECO:0000259|PROSITE:PS50309"
FT DOMAIN 197..265
FT /note="Doublecortin"
FT /evidence="ECO:0000259|PROSITE:PS50309"
FT DOMAIN 494..571
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT REGION 24..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 65221 MW; E95ABB8A65EB7D32 CRC64;
MSDPDNGDTT LPWSSSRSTL DYHSTPDITN LRRTPVPPNV SSFVNRHTQN DRSLNRSFTR
PYATKTVFFY KEGDIYFTGL RVPVSKSRYR TIESLLDDLN CNISIPFGVR YLTTPRGKTI
IKNIDQLQHR GRYIASSFKT PRPLNLSVVE KIQRIRRANR IHAPHYYRNN CFNCRKENKN
EGSKMRLKLS LQPVTSKQIF FVLNGKPSRI YRMQLNSFRQ QTIESLLEEI SRGLQAEIFK
LYTYSGRRII TMDEIYSLNE TRLLAVPRNE RPMFRESMLQ AGVPPLPSIS STPPSLLEQL
VTAKQTIQST NQENSIERPQ RVVSNSKMMP LTSISHQSRR DNNDPKDART INKMEKSSAF
KSLQGSLETY LPTLPISQRS SETSEKATAL QYYEDCCDKN NEPATTGIRA EEESCEKSKQ
IEPESEQETE EHEVDKQKEN TIYTEQSDPM AVEDVPKVTC AATPSEPLFD NSEMTSTSVP
EADNLSPSAK EDGMTYTVSV ITGNRWAADT DLDLFIILYG DLNTSGKHLL RQDTREPKFQ
QSRMDSFHIE TAKLGLLQKI IIGHDRVGYV P
//
