ID   A0A3P6UCK6_LITSI        Unreviewed;       173 AA.
AC   A0A3P6UCK6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Heme-copper oxidase subunit III family profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NLS_LOCUS3381 {ECO:0000313|EMBL:VDK76728.1};
OS   Litomosoides sigmodontis (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX   NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK76728.1, ECO:0000313|Proteomes:UP000277928};
RN   [1] {ECO:0000313|EMBL:VDK76728.1, ECO:0000313|Proteomes:UP000277928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the HRG family. {ECO:0000256|ARBA:ARBA00006203}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UYRX01000181; VDK76728.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P6UCK6; -.
DR   Proteomes; UP000277928; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR026218; HRG.
DR   PANTHER; PTHR31525; HEME TRANSPORTER HRG1; 1.
DR   PANTHER; PTHR31525:SF1; HEME TRANSPORTER HRG1; 1.
DR   Pfam; PF16954; HRG; 1.
DR   PRINTS; PR02095; TRNSPORTRHRG.
PE   3: Inferred from homology;
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..173
FT                   /note="Heme-copper oxidase subunit III family profile
FT                   domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018145350"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        62..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        137..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   173 AA;  20064 MW;  6E486A235349FE81 CRC64;
     MIRLICLLLL LNINTDLPLK SDWTTMTLTW KMKVRLFWPM IGILSGIMAG LSFTIIYHNW
     SAAVMAFISS ISAVNLLLIH RRHIMGTMLM LSESKVKFIF AINCILSILC FVGVIVCLTL
     AATWHQSLSP KDLKKENLWI TAVWFFMTFK WFILSVWYIH RYTSQQSTEQ LLS
//