ID   A0A3P6UF56_LITSI        Unreviewed;       489 AA.
AC   A0A3P6UF56;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=ZZ-type domain-containing protein {ECO:0000259|PROSITE:PS50135};
GN   ORFNames=NLS_LOCUS3434 {ECO:0000313|EMBL:VDK76904.1};
OS   Litomosoides sigmodontis (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX   NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK76904.1, ECO:0000313|Proteomes:UP000277928};
RN   [1] {ECO:0000313|EMBL:VDK76904.1, ECO:0000313|Proteomes:UP000277928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; UYRX01000187; VDK76904.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P6UF56; -.
DR   STRING; 42156.A0A3P6UF56; -.
DR   Proteomes; UP000277928; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd02340; ZZ_NBR1_like; 1.
DR   Gene3D; 3.30.60.90; -; 1.
DR   Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR   InterPro; IPR000270; PB1_dom.
DR   InterPro; IPR009060; UBA-like_sf.
DR   InterPro; IPR000433; Znf_ZZ.
DR   InterPro; IPR043145; Znf_ZZ_sf.
DR   PANTHER; PTHR15090; SEQUESTOSOME 1-RELATED; 1.
DR   PANTHER; PTHR15090:SF0; SEQUESTOSOME-1; 1.
DR   Pfam; PF00564; PB1; 1.
DR   Pfam; PF00569; ZZ; 1.
DR   SMART; SM00291; ZnF_ZZ; 1.
DR   SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF46934; UBA-like; 1.
DR   PROSITE; PS01357; ZF_ZZ_1; 1.
DR   PROSITE; PS50135; ZF_ZZ_2; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00228}.
FT   DOMAIN          108..158
FT                   /note="ZZ-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50135"
FT   REGION          280..338
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..338
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  54282 MW;  370123FDBBAE523A CRC64;
     MAAKNVVNIK WEHFGTFRRF QLPVDADDLY KLLLMKINAV APDFTGKLGW EDEEGDLIYF
     STDDELRGAL QTVANNQLRI QTIAERPKRE EKLEKDTKKE NKKVKEIHPF VTCDHCDQPL
     YGIRYKCSVC DDFDLCEECE KDGTHPDHAL IRYATPRTPK VEHLRPRRTW RQRNHGFGHP
     DPFLQEGIFG RTAAAAAQAA QNAATAAAQH AARHAARHAA AVATHLAENT KENADGLSPQ
     FRESVAQGME YLKEVGSQIQ QALANFGIEV DIDEQHDSVS AKIPKAQDSG AGDAAENATN
     NTTNSKTESV HDEDKKNISK IGEHENEDGK RKSDNPTAEA ILDELDVPMK KMHISESKEI
     EKVVQNSKEP TLDLVSSGDD ISDEWTMMDI GNPGSKCQSG APLYPIDGGK CIAGTPFIVP
     KPGPHNPHCY FIYPDEQVAL CVVQLEAMGF DNCNGWLTKL AADLKGDVSA VIEDMKKDPV
     YAKHFENDI
//