ID   A0A3P6UTL5_LITSI        Unreviewed;       834 AA.
AC   A0A3P6UTL5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN   ORFNames=NLS_LOCUS5058 {ECO:0000313|EMBL:VDK80811.1};
OS   Litomosoides sigmodontis (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX   NCBI_TaxID=42156 {ECO:0000313|EMBL:VDK80811.1, ECO:0000313|Proteomes:UP000277928};
RN   [1] {ECO:0000313|EMBL:VDK80811.1, ECO:0000313|Proteomes:UP000277928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UYRX01000356; VDK80811.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P6UTL5; -.
DR   STRING; 42156.A0A3P6UTL5; -.
DR   Proteomes; UP000277928; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR024789; APC4.
DR   InterPro; IPR024977; Apc4-like_WD40_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR13260; ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4; 1.
DR   PANTHER; PTHR13260:SF0; ANAPHASE-PROMOTING COMPLEX SUBUNIT 4; 1.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   SUPFAM; SSF117289; Nucleoporin domain; 1.
PE   4: Predicted;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          33..131
FT                   /note="Anaphase-promoting complex subunit 4-like WD40"
FT                   /evidence="ECO:0000259|Pfam:PF12894"
SQ   SEQUENCE   834 AA;  94881 MW;  A326D3B4F6E0C463 CRC64;
     MDSICMSNHY VSSDLMGKTV LTRRSPFKVH QALWNPSIDL LTLASQKGEV CVRRLHWRHG
     WKRDIYDVKP LLLDLVKSEG EIRLETMCWS PDGKILATAF SDGCIHLLDA EKGIVRFTVR
     MKTRVTRMRW QRFNQEFNMN LINEDALSGA LGDLSENESL NDKSEELNQL RAMKAFCDSS
     NLSVLGTLLF ALNVDNSVII LAAGVLPIAS VEPPFHLFGN CDPYSITVGD MFYSSKRDQL
     IVVYSSRGQL NPASSSGMNT QVISFDIDSL GYLKNGLIWT IARRWLKLVF CVCFISEAFA
     RAIVDWEDQS KEFIEKFSSF GEENTSNCCL GEYFINMILT GQTSPELVSF YRNVLKPTEW
     KKMTDWTNKG FGDIIESIGR ELLPGAEALQ HNMKQLFIEA RCALYSCRTE KLLPKRLFDV
     DVYPYGKYAE ENEESSLQEL KSFQNLAEDI INKINEMHLV ATRNRKDLVS FTSWLSQTPP
     FTARNKRPAA KMKFDLQLII EYIKQTTIAK NGNAPEGNES MVNTFQNYSF DKVLQYFHRQ
     KPLKYHLDVR SNSWNLLSEQ RSSRTLADSI TSCFDVLQII QDIFLKNFTA AVTAKANLVL
     EQSHAEGFEK FAIFLPNENA STTCTYDEQR WLSTIVDEPF SVSCIGVNGS RHIIYGASSK
     VLYEISYSKG YIKNVASFGK DVKAILSENS ESRSFQVKID GIKLSSDEQQ LQKIGKSTKG
     VDNVMDASGC SESYVSFAVS FHRKSGVVFT ENGFRAKWFD IQIPLQTDLI VNRNQSISGI
     HESNQMKNLI TEAMDVTEQL HVEEGLVVEQ REEEGMRESV QLRRSVRKRK PLKK
//