ID   A0A3P7CJW2_SCHSO        Unreviewed;       397 AA.
AC   A0A3P7CJW2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=ATP receptor {ECO:0000256|ARBA:ARBA00031974};
DE   AltName: Full=Purinergic receptor {ECO:0000256|ARBA:ARBA00033052};
GN   ORFNames=SSLN_LOCUS7511 {ECO:0000313|EMBL:VDL93896.1};
OS   Schistocephalus solidus (Tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Diphyllobothriidea; Diphyllobothriidae; Schistocephalus.
OX   NCBI_TaxID=70667 {ECO:0000313|EMBL:VDL93896.1, ECO:0000313|Proteomes:UP000275846};
RN   [1] {ECO:0000313|EMBL:VDL93896.1, ECO:0000313|Proteomes:UP000275846}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NST_G2 {ECO:0000313|EMBL:VDL93896.1,
RC   ECO:0000313|Proteomes:UP000275846};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the P2X receptor family.
CC       {ECO:0000256|ARBA:ARBA00009848}.
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DR   EMBL; UYSU01034177; VDL93896.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P7CJW2; -.
DR   STRING; 70667.A0A3P7CJW2; -.
DR   Proteomes; UP000275846; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0098794; C:postsynapse; IEA:GOC.
DR   GO; GO:0004931; F:extracellularly ATP-gated monoatomic cation channel activity; IEA:InterPro.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; IEA:InterPro.
DR   GO; GO:0033198; P:response to ATP; IEA:InterPro.
DR   Gene3D; 2.60.490.10; atp-gated p2x4 ion channel domain; 2.
DR   InterPro; IPR027309; P2X_extracellular_dom_sf.
DR   InterPro; IPR001429; P2X_purnocptor.
DR   PANTHER; PTHR10125; P2X PURINOCEPTOR; 1.
DR   PANTHER; PTHR10125:SF31; P2X RECEPTOR E; 1.
DR   Pfam; PF00864; P2X_receptor; 2.
DR   PRINTS; PR01307; P2XRECEPTOR.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275846};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        48..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   397 AA;  45436 MW;  68FF7BD82EF2A647 CRC64;
     MTKAKRRQHK RPRRDVIMGW WNELTSSMFD YETQKVVQIN SKKIGCTFRL IQLGIILYVI
     IWVMIYEKGY QSFDEAVSGV TAKLKGVAFA NLTNNSNIGA MVWDAADYVI PPQQRSAFFV
     MTNLVITPGQ TLGACEEAHD VYGNDCQSDA DCQAGNIVML GSGVQTGNCV KRRNILSWMD
     KKFLFTCRYN PYDEKMKYCP IFSLGDIMNY TDAENKEIWR QGGMVSIHIE WNCNLDFDEE
     QCLPKYVFRR LDDFDSIVGK GWNFRYSYHY MENGTRMRNL IKAYGIQFFI TVYGKGGKFN
     MLTFSMNLGS GLALLGIATV LCDMIVLNVT RKRNLYRDAK VDLVAQQKKL VKKRYLQFAE
     SQCDQKHRGS EEGMNSECRS RDDCEACFVV GSSASGE
//