ID   A0A3P7FG12_WUCBA        Unreviewed;       376 AA.
AC   A0A3P7FG12;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Nematode cuticle collagen N-terminal domain-containing protein {ECO:0000259|SMART:SM01088};
GN   ORFNames=WBA_LOCUS2878 {ECO:0000313|EMBL:VDM09492.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:VDM09492.1, ECO:0000313|Proteomes:UP000270924};
RN   [1] {ECO:0000313|EMBL:VDM09492.1, ECO:0000313|Proteomes:UP000270924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Collagen polypeptide chains are complexed within the cuticle
CC       by disulfide bonds and other types of covalent cross-links.
CC       {ECO:0000256|ARBA:ARBA00011518}.
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DR   EMBL; UYWW01000875; VDM09492.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P7FG12; -.
DR   InParanoid; A0A3P7FG12; -.
DR   OMA; NDAWLEM; -.
DR   Proteomes; UP000270924; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   Gene3D; 1.20.5.320; 6-Phosphogluconate Dehydrogenase, domain 3; 2.
DR   InterPro; IPR002486; Col_cuticle_N.
DR   InterPro; IPR008160; Collagen.
DR   PANTHER; PTHR24637:SF236; COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24637; COLLAGEN; 1.
DR   Pfam; PF01484; Col_cuticle_N; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   SMART; SM01088; Col_cuticle_N; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000270924};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          8..58
FT                   /note="Nematode cuticle collagen N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01088"
FT   REGION          106..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          158..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          349..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..124
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..178
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..243
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  40037 MW;  2F106CF4F9B726E0 CRC64;
     MKRAHFWVCT LSVVSLLVII ASLIICAVLF HDVNTLYYEI LDGMDEFKTI TNDAWLEMMK
     YHAVKNKRYA DSTSKLTLSE LFRTKRIQRQ AYDNHIMRSQ CACSSQPNTC PPGPQGPPGI
     PGTPGIDGEP GLPGKPGING TAFLHNLGLD EYRTCIECPA GPEGPPGEPG PMGEEGPPGM
     PGKPGSDGNP TMAGERGPIG EQGLPGPPGP IGPPGKMGES MLVMYGTPGP KGPPGPEGPI
     GPPGEDGEPG LEGDRGLAGE QGPPGTSGPP GQEGLPGEPG EPGTPGVDAA YCPCPQRTSY
     VYVESAEPSS KPHNFKETEV YTPGEAQLLP SDEYFHALLQ PDHTYVRYKK SQRNRHLLNK
     VTRKKTVSNR KSKKTS
//