ID A0A3P7M564_LITSI Unreviewed; 713 AA.
AC A0A3P7M564;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=SSD domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=NLS_LOCUS9359 {ECO:0000313|EMBL:VDM91541.1};
OS Litomosoides sigmodontis (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX NCBI_TaxID=42156 {ECO:0000313|EMBL:VDM91541.1, ECO:0000313|Proteomes:UP000277928};
RN [1] {ECO:0000313|EMBL:VDM91541.1, ECO:0000313|Proteomes:UP000277928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR EMBL; UYRX01001533; VDM91541.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P7M564; -.
DR Proteomes; UP000277928; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003392; Ptc/Disp.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR PANTHER; PTHR10796:SF187; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000277928};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 578..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..660
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..696
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:VDM91541.1"
SQ SEQUENCE 713 AA; 81390 MW; 8073E48E7D4AD9EF CRC64;
MIGSTTKSPY LQYMSFVLAA GVAILLTFAL LFFPVFLYVA GRRETKGVKW YQCFRSGDTH
FAPRTINEFS IPSIEMLHEK LVDRKPSFSR ALAAAMANSY LRCPVAFIFA IYLVLAIWGC
KDVRIDLKEE YFLSKESESR IFLENYRMEF GQYEEFLELV FDEPIDYLDP HRKDEILAML
EWPIQNQLAT RTVSWLKDFV RFETTTIYDI NPDTFVPIIG IVFLTAENYK KYQNDIIFDK
FQTRIIGSRM YIELTAKGVR ERLFVIDELL NKARSSGISM FIKTPFVFAI QHDLQVMSTV
IIAFTLLLCC VCTLSLFLFG IPSLTVLILL CNLSVIVGVI GFATYWMIPI NAITLFMALA
GNALTTTIVA YFCYNFATAG KTQKTGEQRS CLLPITLACF VPVVTYTPLL LAGLPVMMHI
FKLLLLTSLI TYVHLLLFLP NMMIFLTEQI PSFFSSLQDV CDECCCYCFD IEEDSGSIYY
IPTGGRTTSQ LNGLAKQYSY ALTVPPNTHG MLLPPPKATG YIPVTATVAP VLVPDMLPYQ
PNSIVNIENY RSTKSRRCEN SENVINLFCS FCLPPSPRVA SNRRTPRRER RRLTADDHSP
NDESIYEEPP SLSSNLPDTH SPMQSHRYEG RKPERRQSHS STSRYILRDE RSSERDSSME
LRSNWKQYLV DGNLRQNTGA LATPSPTLTP QPMMYSTPAY RAQPPRYSRD KRF
//
