ID A0A3P7M7R3_LITSI Unreviewed; 302 AA.
AC A0A3P7M7R3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
DE Flags: Fragment;
GN ORFNames=NLS_LOCUS9806 {ECO:0000313|EMBL:VDM92481.1};
OS Litomosoides sigmodontis (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Litomosoides.
OX NCBI_TaxID=42156 {ECO:0000313|EMBL:VDM92481.1, ECO:0000313|Proteomes:UP000277928};
RN [1] {ECO:0000313|EMBL:VDM92481.1, ECO:0000313|Proteomes:UP000277928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; UYRX01001965; VDM92481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P7M7R3; -.
DR STRING; 42156.A0A3P7M7R3; -.
DR Proteomes; UP000277928; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00059; FH_FOX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF399; FORKHEAD TRANSCRIPTION FACTOR FKH-9; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000277928}.
FT DOMAIN 117..212
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 117..212
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:VDM92481.1"
FT NON_TER 302
FT /evidence="ECO:0000313|EMBL:VDM92481.1"
SQ SEQUENCE 302 AA; 32202 MW; C2F381FE477F1DC3 CRC64;
MDLIGSAVLG NSDNSNSNSN SNSNSDSNSS SDNTVNITSS KLDIQNSDDN KSMESVKSES
MMPLIDELAT VSPSSSNVEQ GSSSTPESRL PRTTSPGGNN NGSATEPSPA MMEKAERPSL
SYKDLIIEAI ESSPEKRLKL NEIYQVIRMT HPYYRLRPDQ WGWQNSIRHN LSLHDCFVKL
PLKQTSASGV VGHFWTVVPE LGDKQTLRRR NRVANRSGAR AASTSAAAAG GQFNGRLSSV
DGTTNGILNC AIGADINGFA DGSGIISDHS GSTSPAHCSF DGTHSIGGTN EFRFSTTDSL
LV
//
