ID A0A3P7WJ73_HAEPC Unreviewed; 905 AA.
AC A0A3P7WJ73;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN ORFNames=HPLM_LOCUS16602 {ECO:0000313|EMBL:VDO60796.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|EMBL:VDO60796.1, ECO:0000313|Proteomes:UP000268014};
RN [1] {ECO:0000313|EMBL:VDO60796.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO60796.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; UZAF01019498; VDO60796.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P7WJ73; -.
DR STRING; 6290.A0A3P7WJ73; -.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR PANTHER; PTHR11219:SF70; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11219; TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR SMART; SM00181; EGF; 6.
DR SUPFAM; SSF51126; Pectin lyase-like; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT DOMAIN 237..269
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 295..331
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 241..251
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 259..268
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 321..330
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 905 AA; 98920 MW; 18E7528D5E35E560 CRC64;
MNSLFLLESL KNVAIRDGWG SGIDFISPAE NIRIENVSVT NGSSYSIHVV EFPLLPLKSL
ALQNVSVTDQ TRGHAGVLVS SGWVEQIDID QSLFARNTVP SLIIGVEVRS LGGIHSRNTT
FVSNQDTVVN IDVGECGSVG VEGNRFEGNN NDGRNGVLMM NASPRVGLSP FPFIFKAFRS
MIFNLNYSGG VCICPADRIG LDCSIMIGCP GNCSGNGVCD ILNKCICYDG WTSADCSTPI
CRFDCHGHGK CVSRDECECN AGWSGQFCDQ IGCVDGSCLH GTCVSSKCQC EEGWRGSRCS
FPICQNCSIN GRCVAPNRCQ CFGGYQGEDC SICRGPVCQT CDFDCVHGTC ERETRTCSCS
RGWSGAACDI CRSGNCQVKS SVLYILPSTA DREDTNVIVN VFGVDFPKTP SQLYTCIFGA
SYAEGRRISS SVVRCRVPKD LNLGRHLFNL APEGSISVIP NFDVRPIHFT VFDSCTPVLC
KGVCIGPLCV CPKGTTGINC EIIEIIPSID WHFIENQKAS VAFEGTPYLV VLPTMPGSLH
RVNSTIDGLQ FDSSRGIIAW DEPLGSNGTY EITKPSARSV GVNTSFWIGV EWEQHLATSK
GCDAYVVPLP YLFLPDGSTD IQRMQLLESN RPRPIALRTR VACDCSQGAR AACRRKYKSA
AACGSAWKRI ADDTVSWSEL LLCISSLESE CPILHRRLKR DIDVMAADGP ADVINHVQFI
FPRDELVGLW NSTVNEWTSG QMDTPGETEG ISYADVKQLI VTADRLQSLT RQNGASDPFS
LLHEYIGQIL TTNDMSFERN TCAAVYIEPL VIYEDSSVTI DVYIENLQNV PAPKPGFAPR
FRLEQRKTSS LTTRGRLRTP TLKKETFLLK MLRGRVGGVV FERITFNLGG GLYLTYQGNG
DHARL
//
