ID   A0A3P7WMN3_HAEPC        Unreviewed;       283 AA.
AC   A0A3P7WMN3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Chloride channel protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=HPLM_LOCUS2448 {ECO:0000313|EMBL:VDO14795.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|EMBL:VDO14795.1, ECO:0000313|Proteomes:UP000268014};
RN   [1] {ECO:0000313|EMBL:VDO14795.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO14795.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; UZAF01005048; VDO14795.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3P7WMN3; -.
DR   STRING; 6290.A0A3P7WMN3; -.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR   PANTHER; PTHR45711:SF6; CHLORIDE CHANNEL PROTEIN; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
PE   4: Predicted;
KW   Chloride {ECO:0000256|ARBA:ARBA00023214};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        203..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   NON_TER         283
FT                   /evidence="ECO:0000313|EMBL:VDO14795.1"
SQ   SEQUENCE   283 AA;  31685 MW;  7AC67F43BD4BAF74 CRC64;
     MNSEQTSLRF RADFPWGIIQ SAWDAGAGWI CVLMVGLAAG ATAGVIDIGA RWMSDLKDGV
     CAGRFWLDRE HCCWSSNDTV YKDSDCSAWL AWPEMLNYYG KNPFFYLLEF LFYVGWAVLM
     ATLAVVFVKA FSKRRIPGVR TVLHSIRLHH PRLPGKGVKY FTLLLGLSLG KEGPMVHLAC
     CIGNIFSYLF PKYGMNEAKK REILSASAAA GVSVAFGAPI GGVLFSLEEA SYYFPLKTMW
     RSFFCALVAG IILRIVNPFG SDQTSLFHVD YMMKWTFVEL IPF
//