ID A0A3P7Y6Z3_HAEPC Unreviewed; 801 AA.
AC A0A3P7Y6Z3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=BPTI/Kunitz inhibitor domain-containing protein {ECO:0000259|PROSITE:PS50279};
GN ORFNames=HPLM_LOCUS18049 {ECO:0000313|EMBL:VDO68607.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|EMBL:VDO68607.1, ECO:0000313|Proteomes:UP000268014};
RN [1] {ECO:0000313|EMBL:VDO68607.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO68607.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAF01020303; VDO68607.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P7Y6Z3; -.
DR STRING; 6290.A0A3P7Y6Z3; -.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd22593; Kunitz_conkunitzin; 6.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 7.
DR InterPro; IPR006150; Cys_repeat_1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR028150; Lustrin_cystein.
DR PANTHER; PTHR46339; PROTEIN CBG15282-RELATED; 1.
DR Pfam; PF00014; Kunitz_BPTI; 7.
DR Pfam; PF14625; Lustrin_cystein; 2.
DR SMART; SM00131; KU; 7.
DR SMART; SM00289; WR1; 2.
DR SUPFAM; SSF57362; BPTI-like; 7.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 7.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT DOMAIN 68..118
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 183..234
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 244..294
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 460..510
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 577..627
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 633..683
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 712..771
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT REGION 150..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 801 AA; 90016 MW; 6E9F6A6D12A2B5D1 CRC64;
MINRIISDYS LLCAEGVPLL MEDHRPRPCQ PRPWLPEHKC PASFWCHEGD DESSYYCCPK
NRKFENRCHL PPATGHGTLS MRRFYYDWMS DGCHELHYTG IGGNENSFMT YESCEEACRG
ELFHVCMLAL VFSSCSKLYP LSKTSTSSVR KVTESATSSS PESYESSPED EQLQTLWQDT
NPCEAPASAG SPGGIARKMW YFDESAISCV PFVFLGSGGN ANRFADQGTC MRTCGSGKPT
RASCELPSQF GNGTFKIPRY YFDKTAKQCE LFYYSGNGGN ENRFLKKAKC ERLCLGSSFN
FFFSFLISSS LVSFPDSASP TTAAAPTPTQ SETSSDQILR KSSSREETNQ NYTSSSEEAT
TLDPFPTLIN IPKGIGQQIL FASSFFRCKI LFQSSYHHSH NFTAALFQQV ALDVSPCQSP
LRGDVVIMCV LDGVTCPAGT FCQVGDAQSI CCPTLPEPQC EQPQRPGVGT STLLRWYYKP
STRQCHMFVF HGFQGNQNNF ESLQECESTC RDLNPCEEGA PLPAIDGSQK ILVFYTFFLF
LFLLPLECSI QSLTRHVLYF RLMKMGLYYW NGMSSECLMP EDAGHGVESS HRWSYDSPTR
KCVSFIYHGY GGNQNNFLSR NDCETACIPT NPCDQPVSSG HGNKFISRFF FSKEYGQCLH
FAYSGEGGNS NNFANLRECV DTCMSNSSYF RCKLISILAF ELLFSKLPES FCLQPRPPLN
VCLSPNSPPV QRIQFTYDPL ADRCVRFSYS SCSPDYNLNH FETDSQCQRL CCNQGYDLVY
KRKLLMLNDS PLDDSEDSDR L
//
