ID A0A3P8N801_ASTCA Unreviewed; 1526 AA.
AC A0A3P8N801;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Immunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 1 {ECO:0008006|Google:ProtNLM};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000000885.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000000885.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000000885.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 8154.ENSACLP00000000885; -.
DR Ensembl; ENSACLT00000000906.1; ENSACLP00000000885.1; ENSACLG00000000512.1.
DR GeneTree; ENSGT00940000160123; -.
DR OMA; VGRNDWE; -.
DR Proteomes; UP000265100; Chromosome 5.
DR Bgee; ENSACLG00000000512; Expressed in muscle tissue and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 11.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR040849; MyBP-C_THB.
DR PANTHER; PTHR13817:SF138; IMMUNOGLOBULIN-LIKE AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR13817; TITIN; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 6.
DR Pfam; PF18362; THB; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 66..157
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 713..804
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 909..1005
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1008..1105
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1108..1209
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1212..1302
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1307..1402
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1420..1508
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 510..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 442..490
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 668..682
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1526 AA; 164676 MW; 60A8ACDA0064958A CRC64;
MTQSSDHRCE NRPVKSAHWT ALENMKQANI CGPLTVFFIG IRKKSKVPGV MITQFMEELP
EGMTTPDFTR KPIALTIQEG KFAFFKAIIV GTPTPTVTWS RANGEILFHP SVCLQKYDEA
THEHTIEFPK VSPEDADTYK CFATNEYGRA VCTVVLNVIE VGFSKTKELQ KAQVEGKNGT
REQKPMETEE KVWEILLSAD KKDYERICAE YGITNFRGML KKLNEMKKER EEEVAEFVTH
ISSLKPIEVT DDDYATIELD MDLKDPSSKL YLYKDGVMVP FSKDEADEQK HSLKQVGKKY
IFKIKKLGVE DAGLYSVDVE GVNVFSTDFK VTPVEFAVKI QEVKAEERED ALFQCVLTAP
MNEIKWYGKS ALLSNSEKHE ITISEDKLIH KLIVRDCMPL DAGIYAAVAG IKSCNAWLIV
EADKDPASKG KKVARKTTMA GGSNEEELLK IAKEQQEKYQ KELEEKLELA KKAQAEKEAA
GAAAQEDEEA AKKAAAEAKA KAKAAARAKR AAAGKDGAPR KSAKKGAGAG SGAASADGTV
GAEGAAGVGG AAGADGTVGA GGAAGVGGAA GAGGADGTVG AGGAGGAVGA RGAAGAGGTG
GPGGAAAVAG AGGTSGIGAG SAGGAGNGVD GGASAGGQEG GHGAAAIGKG GAQGAAGVGV
GGEFEGEWGE EGCVEGGGEE GEGGEGGEGG VGGEGGGKGG KRRKRVRAGP LVPDTVIDPG
VHFHAGLSDC KAIIGEAAEL ECKVSSEDCV GVWYKDGEEI KSSEGLTISK DGTFHRLKIH
KVTEEFAGKY KFEADGRKTE AEIAVEDPPR FNAEDLEAFK TPVTVKKGHK ATFNLAFIGR
EPIKIQWYRE GEELSEEANI KIEHSEGSSR LLLLKLQRKD SGEIKIKLKN EFGTMEALSQ
LVVLDKPTPP MGPLEIVEAS SSAVEFKWRP PKDSGGCKIL NYILERQQVG RNTWKKFGPI
GPEAKYRDTD VDHGRRYCYR LRVETEMGIS ELMETEDIQA GTKAYPGPPS APKVVSAFKD
CITLSWSPPA DTGGTSILGY NLEKRKKGSN LWGPVNPPNE MIRGKQFAVK DVVEGMEYEF
RVSAINNSGA GEFSSPSEFV FARDPKKPPG KVSDFKVTDS TYTTISLSWT KPKDIEGVED
EAKGYFVEIR LAENTEWDRC NLNAITMTSY TVKGMKSMAM YWVRVIAINE GGHGEPQELD
NYHISMPPPV RPRFTDAKIK SFMVVRAGNS ARFNINFEAS PWPDVIWLKD GVPVSKKVTI
SNAEGTSQIL IPSAERSDTG VYTIIVKNIV GQETISIEIR VTDEPKPPGP VELDENVHGT
VTISWTASPD EKRDDRLHYM VTKRDSSKRT WNTIADRIFN NRFTACNIMP GREYQFRVYA
KNDMGSSKPS ESPKWLIPAK KEKFTVKMPE SKTCNLLCPP KFIVPLKTHT APEGYECYMT
CAIKGDPTPH VTWLRDSVSL NTNTNYLISN TCGVCSLLIL RVGSKDTGEY KVVAENSLGR
AESATKLTVR GKPFKETFYA FPHLLS
//
