ID   A0A3P8N8T0_ASTCA        Unreviewed;       163 AA.
AC   A0A3P8N8T0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Fucolectin tachylectin-4 pentraxin-1 domain-containing protein {ECO:0000259|SMART:SM00607};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000001167.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000001167.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000001167.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Acts as a defensive agent. Recognizes blood group fucosylated
CC       oligosaccharides including A, B, H and Lewis B-type antigens. Does not
CC       recognize Lewis A antigen and has low affinity for monovalent haptens.
CC       {ECO:0000256|ARBA:ARBA00002219}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000256|ARBA:ARBA00011233}.
CC   -!- SIMILARITY: Belongs to the fucolectin family.
CC       {ECO:0000256|ARBA:ARBA00010147}.
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DR   AlphaFoldDB; A0A3P8N8T0; -.
DR   STRING; 8154.ENSACLP00000001167; -.
DR   Ensembl; ENSACLT00000001196.1; ENSACLP00000001167.1; ENSACLG00000000830.1.
DR   GeneTree; ENSGT01060000248575; -.
DR   OMA; FQGYPLP; -.
DR   Proteomes; UP000265100; Chromosome 3.
DR   GO; GO:0042806; F:fucose binding; IEA:UniProt.
DR   GO; GO:0010185; P:regulation of cellular defense response; IEA:UniProt.
DR   GO; GO:0001868; P:regulation of complement activation, lectin pathway; IEA:UniProt.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR006585; FTP1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR45713; FTP DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45713:SF8; V-FBPL-RELATED; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   SMART; SM00607; FTP; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Lectin {ECO:0000256|ARBA:ARBA00022734}.
FT   DOMAIN          18..157
FT                   /note="Fucolectin tachylectin-4 pentraxin-1"
FT                   /evidence="ECO:0000259|SMART:SM00607"
SQ   SEQUENCE   163 AA;  18191 MW;  506622D9E8FE6AD8 CRC64;
     MMNLYQLSPC VKWRCMLPQQ SSTWYGPVFG PSKGVDGCKN GNLDSGCCTH NDQDLGPWWR
     VDLQAVYKVS AVTIINRQDG YIPRILGAQI LIGNSLEQNG NQNPSCGMIK SLDGTPTYTF
     QCNEMEGRYI IVIIPGKNTY ATLCEVEVFT RGSQGSNHRL YDK
//