ID   A0A3P8N992_ASTCA        Unreviewed;       250 AA.
AC   A0A3P8N992;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000001343.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000001343.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000001343.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
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DR   STRING; 8154.ENSACLP00000001343; -.
DR   Ensembl; ENSACLT00000001375.1; ENSACLP00000001343.1; ENSACLG00000000955.1.
DR   Ensembl; ENSACLT00000001404.1; ENSACLP00000001371.1; ENSACLG00000000955.1.
DR   GeneTree; ENSGT00940000159092; -.
DR   OMA; FLFRHEI; -.
DR   OrthoDB; 2913577at2759; -.
DR   Proteomes; UP000265100; Chromosome 2.
DR   Bgee; ENSACLG00000000955; Expressed in ovary and 8 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070925; P:organelle assembly; IEA:Ensembl.
DR   CDD; cd03161; TM4SF2_6_like_LEL; 1.
DR   Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   InterPro; IPR048232; TSN6/7_LEL.
DR   PANTHER; PTHR19282; TETRASPANIN; 1.
DR   PANTHER; PTHR19282:SF426; TETRASPANIN-32; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM        21..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        62..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        92..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        214..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
SQ   SEQUENCE   250 AA;  27713 MW;  F970612D629AC5A1 CRC64;
     MSPPSRRLQT KPVITCLKTF LISYSLIFWV TGVILLAVGV WGKVSLETYF SLAAEESTNA
     PYVLIGTGAI IVIFGLFGCF ATCRGSPWML KLYAMFLTLV FLAELVAGVS GFIFRHEIKA
     TLDNGYKNAV IKYNGTESKN PVDTIQRNLH CCGVYNYTDW NNTKYFQEKG IPVSCCKDSD
     NCSPETLKDL AKAENVVYTT GCFVLVSTTM ENNLGIIAGI SFGIAFFQLI GMFLACCLSR
     YITNNQYEMV
//