ID   A0A3P8N9H5_ASTCA        Unreviewed;      1995 AA.
AC   A0A3P8N9H5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Fc fragment of IgG binding protein {ECO:0000313|Ensembl:ENSACLP00000001415.1};
GN   Name=FCGBP {ECO:0000313|Ensembl:ENSACLP00000001415.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000001415.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000001415.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000001415.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSACLT00000001448.1; ENSACLP00000001415.1; ENSACLG00000000719.1.
DR   GeneTree; ENSGT00950000183155; -.
DR   Proteomes; UP000265100; Chromosome 11.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd19941; TIL; 5.
DR   Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR   Gene3D; 2.10.25.10; Laminin; 5.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   InterPro; IPR025615; TILa_dom.
DR   InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR46160; ALPHA-TECTORIN-RELATED; 1.
DR   PANTHER; PTHR46160:SF4; VWFD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF08742; C8; 5.
DR   Pfam; PF01826; TIL; 5.
DR   Pfam; PF12714; TILa; 5.
DR   Pfam; PF00094; VWD; 5.
DR   SMART; SM00832; C8; 5.
DR   SMART; SM00214; VWC; 4.
DR   SMART; SM00215; VWC_out; 5.
DR   SMART; SM00216; VWD; 5.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 5.
DR   PROSITE; PS51233; VWFD; 6.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..46
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          255..439
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          674..856
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          1067..1243
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          1453..1613
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          1819..1995
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
SQ   SEQUENCE   1995 AA;  217051 MW;  922204EC882710B5 CRC64;
     MGAVCGLCGN YNGKPEDDLI PKNGKTPVSP VDFGTSWRVA EIPGCVEGCK GVCPDCDINQ
     KVQYEKDDFC GVVKDAKGPF RDCHAKVDPA SFFEDCVYDV CLYKGRKDVL CKAITAYTSA
     CQAAGANVYN WRTVHFCAMQ CPTNTHYEIC AIACPVTCQS LTPPKGCQAQ CAEGCSCDDG
     YILSGDACVP LSECGCVHNN RYYRTGEVFY PNGQCEEECN CKKGGEVECK KFTCGPNEKC
     KIEDGVQKCH PVGKGVCQAA GDPHYLTFDG KKFDFQGTCT YTLSKSCGLE GTHLVDFSVQ
     VENEQWDRVK NRKVVSVTKL VAVEVYGFTL IMRNNMFGVL VNGVLSYLPM NLNDGAILVY
     QEGNRYVIAT NFGLLVTYDL VYQVTVTVPG NYRGKVCGLC GNYNGDRNDD FEMPNRRLTN
     NVNEFGKSWK VTIPNVVCEN GCEGNSCPEC DPALKAVFSK SAYCGIMTNP NGPFAVCHSI
     LDPQPYFADC VFDLCASNGD GKVLCDSVAA YAFNCHAVGA DVKNWRTPSF CPMKCPINSH
     YEVCAEACSA SCAGLTEIVQ CPSNCTEGCD CDAGFLFNGQ TCVKEIECGC YENGKTYKPG
     DVVYEEDCNR KCTCNPGKGL ICEKHSCPQD TKCMVKNGIR ACYNTDPCKD LKCRAQETCR
     VEKGEATCIP KYTGTCWAWG DPHYHTFDGY NYDFQGTCKY VISKTCGELD GLVPFLITER
     NDNRGNTAVS YVRNVDVFVY DYQITIQKNQ VGQVMVDGEL LNLPVLLGDG KVSVLQRGNT
     AQVETDFGLV VSYDWNWYLV IKLPSSYFGL VCGLCGNFNA NVLDEMLNPA GKPVSSVIEW
     GKSWLAPEQD KEHPCWDTCE KNCPTCDNDD VKLYKTEAFC GALADKTSGL FQKCHEKVDP
     QAFMNNCVYD MCYNKGDKKM LCQALASYSD KCRDEGIIIK NWRTKFGCPM NCPRNSHYED
     CASPCQPSCP LTGEKQVCSG TCVETCVCDE GYVLSAGVCV PAKTCGCSYQ GRYYKPGQQF
     WDDEACHRLC ECDMTLGIVA CREASCSAKE QCTVVDGERA CRPISYATCS ASGDPHYRTF
     DGRRYNFQGT CVYQLAGLCS QQPGLVPFKV TVQNDHRGSK AVSYTSTVKF SIYGITLTIS
     REYPYKLDGQ LVLLPLNYNN ELMVSLSGWK AVVETAAGIT VTFDWQSTVT VTLPSTYQGA
     VCGLCGNYND KAQDDLTMPN GNTTSNERQL GDSWQVAIVP GCSSVCQGPW CQACSDSQKK
     VYEANKYCGI IADKAGPFKD CHSRVDPAPY MEDCVFDVCQ YQGHHGSVCD AVEVYASACQ
     SIGVTIYSWR AESFCPMACP ANSHYSLCAT GCPATCASLT PVTSCHRYCS EGCECDEGYL
     LSGDTCVPVK DCGCSYDGQY YQKGDVFYSE DKCAEECTCG DNGAVSCQKA KCRPGEICKL
     VNGVKGCYPE GEGKCVASGD PHYISFDGRR FDFQGTCVYV LAKVCDDDKG QLTPFTVTQG
     NEKFGNGKVA VTKSVDDELL NLPLSLENGR LKITQEGRNI IVRTAFGLTV LYDTVYYVEV
     IVPSTYQGKM CGLCGNYNKN GGDDFILPGG KQAKNVDEFG MAWTVDLPGY ICGGCGGQCP
     ECEQAKAVLY GKSDSCGIIS APNGPFKACH SVIDPAVYLS DCVFDVCAVG GNKDTLCNSV
     QAYALACQSA GVQIQQWRSN SFCPASCPPH SHYELCADTC SGTCASFVTP FGCFPGCFEG
     CQCDDGFVFN GVQCVVLEDC GCMYNGRYLM VGQELVDNDC KSKCVCQASG MVKCEKLSCA
     SGEVCDIRDG VRGCHLKQGQ CVVSRDGQLS SFDGMSGAIG AQGAFQVASL CDESAELWFR
     VVVDVRVCNK GAAPTVASVY VFFSDTIVAV NSEHVTWVNG RKVSLPSKVT STLSVQISER
     ALIIERASTV RVTYSISQEV TVIIHSSLSG KMCGACGNYN NNSKDDMTTA LLFHLSTTHF
     GVATADYLAS ILPCP
//