ID A0A3P8N9V1_ASTCA Unreviewed; 359 AA.
AC A0A3P8N9V1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Neuronal growth regulator 1 {ECO:0000313|Ensembl:ENSACLP00000001484.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000001484.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000001484.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000001484.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC {ECO:0000256|ARBA:ARBA00004589}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. IgLON family.
CC {ECO:0000256|ARBA:ARBA00037995}.
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DR AlphaFoldDB; A0A3P8N9V1; -.
DR STRING; 8154.ENSACLP00000001484; -.
DR Ensembl; ENSACLT00000001517.1; ENSACLP00000001484.1; ENSACLG00000001022.1.
DR GeneTree; ENSGT00940000159289; -.
DR OMA; TFKCIVV; -.
DR OrthoDB; 5394513at2759; -.
DR Proteomes; UP000265100; Chromosome 15.
DR Bgee; ENSACLG00000001022; Expressed in brain and 3 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR42757; IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED; 1.
DR PANTHER; PTHR42757:SF9; NEUROTRIMIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor {ECO:0000256|ARBA:ARBA00022622};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..359
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017968149"
FT DOMAIN 33..132
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 139..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 225..312
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 359 AA; 38676 MW; 8044F238F52620A2 CRC64;
MDIMTAVQDA CVSGQWLTAI ILSLCCFLPS CLPAGQTVDY SSVESVVSRQ GDTALLRCYL
LDGISKGAWL NRSSIIFAGN DKWSVDPRVS IVSSVGDKHE YSLQIQKVDV TDDGLYTCSI
QSERNPRPKL LNLIVKVPPK IYDISPDITV NEGSNVSLIC TASGKPEPTI TWRHITPLAK
KYDSGENLNI TGITKDQAGD YECSALNDIA SPDTKRVKVT VNFAPSIHDI KSHGVGLGRT
ALLRCEAAAM PSPTFEWYKG EKRIIKGQGI DIKSLSSRSV LTVTNMTEDR YGNYTCVASN
KLGTANASVP LNPIIEPTTT SAVSSPAPNT APYGSTGSAH ISLACRYLVM ALSSFISVY
//
