ID A0A3P8NA38_ASTCA Unreviewed; 634 AA.
AC A0A3P8NA38;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Actin binding LIM protein family, member 3 {ECO:0000313|Ensembl:ENSACLP00000001626.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000001626.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000001626.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000001626.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A3P8NA38; -.
DR Ensembl; ENSACLT00000001661.1; ENSACLP00000001626.1; ENSACLG00000001009.1.
DR GeneTree; ENSGT00950000182850; -.
DR Proteomes; UP000265100; Chromosome 2.
DR Bgee; ENSACLG00000001009; Expressed in camera-type eye and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09328; LIM2_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR032402; AbLIM_anchor.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF0; ACTIN-BINDING LIM PROTEIN 3; 1.
DR Pfam; PF16182; AbLIM_anchor; 1.
DR Pfam; PF00412; LIM; 4.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 4.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 5.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 3.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 20..79
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 80..139
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 149..208
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 566..634
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
FT REGION 319..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 476..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 634 AA; 71452 MW; 5571404EB0CEB78A CRC64;
MSSSAYRQDS TGGQRSSGPI RCQRCREVCK GEVVRVQETH FHVKCFTCTV CNCDLAQSGF
FQKKGEYICT ADYQRLYGTR CDRCDTFITG EVVSALGRTY HPKCFVCSVC SKPFPIGDRV
TFSGKDCVCQ QCSHTLVKSN EPIKIHGPSH CAGCGAEIKQ GQSLLALDKQ WHVSCFRCRT
CNMVLTGEYI SKDGVPYCEA DYHAQYGVKC ETCSRYISGR VLEAGGKHYH PTCARCARCN
MMFKEGEEMY LTGCEVWHPL CKQAARAERR LRHRRLSEAS ISPPGSSIGS PSRVICSLGT
LSPYSQDYNS LDIKQRRCSS PGYIDSPTYS RQGMSPIMPR SPQHYGYPGS ESGRSSPYYS
QDGRPSTPTT NQPPKHFHVP ATGDPNIYRK PPIYKRTATK SRTSEDILRS SRLSTYSPEP
YSQSESDYYP YSSSPRAYRA PRRRFSTGGD EETWSHGLQR IGSGIGRMIL KEEMKARSGS
YDNDPWGSAR NSRSGSKETL NTTSYGTTAY NNTINGSPRS QYSTDSDFVC KSASLPGYGR
NGIQRPQSAD CYQYQYDSGS EVNWGSREHK IYPYESLIVT TRGRNRLPKD VDRARLERHL
SPEEFVQVFG MTVEEFDRLA LWKRNELKKQ ARLF
//
