ID   A0A3P8NB69_ASTCA        Unreviewed;       409 AA.
AC   A0A3P8NB69;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Methyltransferase like 4 {ECO:0000313|Ensembl:ENSACLP00000001939.1};
GN   Name=METTL4 {ECO:0000313|Ensembl:ENSACLP00000001939.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000001939.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000001939.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000001939.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MT-A70-like family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00489}.
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DR   AlphaFoldDB; A0A3P8NB69; -.
DR   STRING; 8154.ENSACLP00000001939; -.
DR   Ensembl; ENSACLT00000001982.1; ENSACLP00000001939.1; ENSACLG00000001329.1.
DR   GeneTree; ENSGT00390000016237; -.
DR   OMA; WVTNRQR; -.
DR   Proteomes; UP000265100; Chromosome 9.
DR   Bgee; ENSACLG00000001329; Expressed in spleen and 1 other cell type or tissue.
DR   GO; GO:0140640; F:catalytic activity, acting on a nucleic acid; IEA:UniProt.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:InterPro.
DR   GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR007757; MT-A70-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12829:SF4; N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4; 1.
DR   PANTHER; PTHR12829; N6-ADENOSINE-METHYLTRANSFERASE; 1.
DR   Pfam; PF05063; MT-A70; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51143; MT_A70; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
FT   REGION          388..409
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   409 AA;  46207 MW;  F67A6463A4AD447A CRC64;
     MSVVLHGSLG WVLDSCSLID RGYSPCIRWR ENQKSALKCS FKRQCFQVFK SYYNENNRAD
     VDAGNTEVLK KTCKPSKVNA IKSVILEGTK YLVDSAQPLG YLNGQTNVDK EPLPSQECNL
     AALCEMAKDL PLVEDEEQER GAQLLVGEDG CTSHVDLFSQ VTENKADWAT VVTVMGEEYV
     IPPHTAFLLS DFTRIQPLVH YGTRFDLIVM DPPWENKSVK RSRRYGSLPS SQLKRLPIPL
     LASPNCLVVT WVTNRPSHLR FVRDELYPHW GVEVVAEWFW VKVTTFGQFV FPLDSPHKKP
     YEVFVLGRYQ TSEVPVEDQR LIVSVPSALH SQKPSLSEVL KPYIGADAKC LELFARSLQP
     GWTSWGNEVL KFQHVSYFNL TPVDEKAEAE DDCTAKEKQA QGFDSPGKT
//