ID A0A3P8NBQ5_ASTCA Unreviewed; 245 AA.
AC A0A3P8NBQ5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000002139.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000002139.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000002139.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P8NBQ5; -.
DR Ensembl; ENSACLT00000002186.1; ENSACLP00000002139.1; ENSACLG00000001432.1.
DR GeneTree; ENSGT00950000183126; -.
DR OMA; GWELPPW; -.
DR Proteomes; UP000265100; Chromosome 23.
DR Bgee; ENSACLG00000001432; Expressed in anal fin and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00185; TNFRSF; 1.
DR CDD; cd13405; TNFRSF14_teleost; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR PANTHER; PTHR46838; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14; 1.
DR PANTHER; PTHR46838:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..245
FT /note="TNFR-Cys domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017969559"
FT TRANSMEM 200..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..109
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 67..109
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 68..83
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 245 AA; 26397 MW; BC0FB72F253CFB2E CRC64;
TSSMMSLWRS GRVVLVILII LMNVFNGLSL TCHQAEYQIG NECCPKCLAG SRVKTHCNEY
RSTSCLPCMD GTFTDQPNGW ERCIPCTNCH PALGLRVKKQ CTATSDTLCK PLEGLYCVHH
TGHSCERAHE HKRCNPGQYI SQNGTASTDT ECSDCSSGTF SNGTFHSCQP HTQCHSLNLQ
QITTGTSAAD AQCGERSFNV GAAVGGAVGV LILIIGGGGL LYWYLKKRPL AMASPEGRTV
SCSLI
//
