ID A0A3P8NCT7_ASTCA Unreviewed; 526 AA.
AC A0A3P8NCT7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=AIG1-type G domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000002597.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000002597.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000002597.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR AlphaFoldDB; A0A3P8NCT7; -.
DR STRING; 8154.ENSACLP00000002597; -.
DR Ensembl; ENSACLT00000002654.1; ENSACLP00000002597.1; ENSACLG00000001777.1.
DR GeneTree; ENSGT01100000263538; -.
DR Proteomes; UP000265100; Chromosome 3.
DR Bgee; ENSACLG00000001777; Expressed in muscle tissue and 5 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR002589; Macro_dom.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF186; GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR Pfam; PF01661; Macro; 1.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
DR PROSITE; PS51154; MACRO; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 417..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..157
FT /note="Macro"
FT /evidence="ECO:0000259|PROSITE:PS51154"
FT DOMAIN 170..379
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
SQ SEQUENCE 526 AA; 57350 MW; 38E2AAFE8CFBB4D4 CRC64;
MVGHDPLSTR VGNALFEVAG PQLTTRFRKE EEDETMPGDS VLLEGLPGLQ SNAVFFLNLV
PWDGDPDGVA VQVLRMGINT ILSSCAKKRF RSVALPVLGA GMALQFPVSE VVRALKEEVH
VFEEEQVGIT PLLIRIVIHP DDEDSHKVFD VFQNDNFTQH VHQKVHDLES TTMRLVLLGK
TGSGKSHLGN TILGEEHFTF YDSPNSGTMK CQTETKTVSG RSITLIDTPG FFDTGRSEED
LKPEIMSCMT ECAPGPHAFL IVLRVDKFTE HEQAVVTKIV QYFSDEALKY AVVVFTHGDQ
LKKKMKIEDF VSQNKNLSDL VSKCDGRCHV FDNKHWNNNQ PNNYRSNQFQ VEELLKTIEK
VVVEKNGGYY TNKMLQHVET AIQKRVEHIS YSMPDKTAEE IRNQAKSDVC NRFLTKLTGI
ATGALLGAFF GVAAMVGLAV TAMNNVMLMN AVKKAPALMG VSSAAAGEAA VGVAGAACVA
VAAAAGGVFG GFIGNEAAND AKSPSDAAQR ACEAIVEKGK SLIRFK
//
